# Limit of Detection Calculator AI Agent Connect

> Calculate LOD, LOQ, and noise profiles using IUPAC-compliant statistical methods.

## Overview
- **Category:** analytics
- **Price:** Free
- **Endpoint:** https://edge.vinkius.com/vk_preview_oSJ2GBk2g3FdcQTvAZZuvZc5QxQONoQmHFGqfNHA/ai-agent-connect
- **Tags:** analytical-chemistry, iodp, statistics, detection-limits, laboratory

## Description

This MCP server provides specialized analytical tools for determining the minimum detectable and quantifiable concentrations of substances. It uses IUPAC-compliant statistical methods to process blank measurements and calibration data. Use `calculate_detection_limits` to find the LOD and LOQ, `analyze_noise_profile` to assess baseline stability, `validate_calibration_parameters` to check statistical validity, and `estimate_minimum_sample_size` to plan your analytical runs.

## Tools

### analyze_noise_profile
Analyze the stability and noise profile of the blank measurements

### calculate_detection_limits
Calculate LOD and LOQ based on blank measurements and sensitivity

### estimate_minimum_sample_size
Estimate the minimum number of blank replicates needed for desired precision

### validate_calibration_parameters
Validate if calibration and confidence settings are statistically valid

## Prompt Examples

**Prompt:** 
```
What are the LOD and LOQ for my measurements: [0.01, 0.02, 0.015, 0.012, 0.018] with a sensitivity of 0.5 and a multiplier of 3?
```

**Response:** 
```
The calculated Limit of Detection (LOD) is 0.0072 and the Limit of Quantification (LOQ) is 0.072.
```

**Prompt:** 
```
Is my baseline stable with these blank measurements: [10.1, 10.2, 10.1, 10.3, 10.2]?
```

**Response:** 
```
Yes, the baseline is stable with a mean of 10.18 and a standard deviation of 0.084.
```

**Prompt:** 
```
How many blank replicates do I need for a target precision of 0.05 if my current noise is 0.02?
```

**Response:** 
```
You need to perform 16 blank replicates to achieve the desired precision.
```

## Frequently Asked Questions

**How is the Limit of Detection (LOD) calculated?**
The LOD is calculated by multiplying the standard deviation of the blank measurements by the confidence multiplier and dividing the result by the calibration sensitivity.

**Can I check if my baseline is stable?**
Yes, you can use the `analyze_noise_profile` tool to evaluate the coefficient of variation and determine if your baseline is stable.

**What inputs are needed for detection limit calculations?**
You need to provide an array of blank signal measurements, the calibration sensitivity (slope), and a confidence multiplier.