UniProt MCP Server

Connect your AI agent to UniProt — the Universal Protein Resource — the world's definitive knowledge base for protein sequence and functional information.

What you can do

• Protein Search — Find proteins by name, gene symbol, function, or organism across 250M+ entries from both TrEMBL (auto-annotated) and Swiss-Prot (manually curated)
• Accession Lookup — Get complete protein data by UniProt accession number (e.g., P04637 for human p53) including function, subcellular location, and full amino acid sequence
• Gene Search — Find all proteins encoded by a specific gene name across multiple organisms to compare orthologs and paralogs

How it works

1. Subscribe to this server
2. Start searching proteins immediately — no API key required

Who is this for?

• Molecular Biologists — quickly look up protein functions, domains, and post-translational modifications for experimental design
• Bioinformaticians — retrieve protein sequences and annotations programmatically for large-scale comparative analyses
• Drug Discovery Teams — identify therapeutic targets by searching protein functions and disease associations