
Connect Codon Usage Optimization to ChatGPT and Claude
Set it up once and it works in ChatGPT, Claude, Cursor, and any other client you love. It all runs safely in the background, so you can relax and focus on what really matters. Convert protein sequences into optimized DNA for specific hosts.
Developed, maintained, and hosted by Vinkius.
MCP VERIFIED · PRODUCTION READY · VINKIUS GUARANTEED
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Works with modern AI clients that support MCP, including ChatGPT, Claude, Cursor, and more.
Your AI does the work. We keep it safe and sound.
No other AI tool gives you this. Your workflow runs in the client you already love, your account stays protected, and you decide what the agent can and cannot do. It is the whole reason to make the switch.
Each Connector lives inside our infrastructure, the same place where your workflow runs. The three things below are already part of it, working quietly in the background so you never have to think about them. Nothing to add, nothing to set up, nothing to worry about.

Each Connector runs inside its own sealed environment.
Each Connector runs inside its own sealed V8 runtime — no access to your files, your system, or other servers. A Connector never sees past its own request.
One switch stops every agent. Instantly.
One action deactivates every Connector, revokes every token, and ends every session at once. AI Governance keeps the record.
Spending limits that pause instead of surprise.
Every user keeps their own connections and credentials, isolated from everyone else. Anything that would cross your spending limit is held for your approval, not billed.
Three controls, built into the layer your AI connects through.
Curated set · 4 capabilities
We ship only the actions that matter.
01-04
4 capabilities in this set.
Part of 4 available through Codon Optimization Service.
- 01
Analyze codon usage
This capability provides a statistical profile of how a DNA sequence uses codons relative to a specific host.
- 02
Validate host compatibility
This capability checks if a protein sequence is likely to work with a host's translation machinery.
- 03
Calculate complexity metrics
Use this to evaluate the physical and structural properties of a DNA sequence.
- 04
Optimize sequence
This capability generates an optimized DNA sequence from a protein sequence based on your chosen expression host.
Real work
What teams actually run
Heterologous Expression
Optimize a protein sequence for expression in E. coli or H. sapiens.
Sequence Validation
Check if a new DNA sequence has the right structural properties for synthesis.
Host Compatibility Testing
Predict if a specific protein will work in S. cerevisiae before starting lab work.
Codon Bias Analysis
Analyze how a sequence's codon usage compares to a target host's profile.
One connector, every AI
Codon Optimization Service works with the most popular AI clients.
These are the most popular clients, each with a step-by-step guide: one link, set up once, with governance and visibility built in. And because everything runs on the MCP standard, the same connection also works in any other compatible client — nothing to rebuild.
Claude
ChatGPT
Gemini
Perplexity
Grok
Microsoft Copilot
Cursor
VS Code
Windsurf
JetBrains
Cline
LangChain
Vercel AI SDK
Lovable
Z.ai
Raycast
Qwen Code
Kimi Code
Le ChatBuilding your own app? The connector is yours to use.
You don't need a client to put Codon Optimization Service to work: the same hosted connection plugs into your own applications and agent code, with the same governance on every request. Build with it, chat with it — one connection for both.
Observed, not estimated
894ms average. Fast in production.
Codon Optimization Service is checked daily against the live service.
- Fastest day
- 725ms
- Slowest day
- 1205ms
- 14-day trend
- Slowing+20%
Connect your client
One URL. Every client.
Activate the Connector, copy your link, and paste it into the client you already use. 4 capabilities arrive ready to run.
Preview access · not provider authentication
The vk_preview_* token belongs to Vinkius preview infrastructure. It lets Claude discover and display the capabilities of Codon Optimization Service, so you can see the experience inside your AI.
It does not authenticate your account with Codon Optimization Service. Actions requiring credentials or live account data may not run until you activate the Connector and authorize the service.
Codon Optimization Service Connector
You're all set. Choose your MCP client and follow the setup instructions.
https://edge.vinkius.com/vk_preview_EwhIYVMAwkqiTjDiRdWlLHasxz10yWoao2pKz7gf/mcpClaude Desktop
Follow the steps below to connect in seconds.
- 1In Claude Desktop, open Settings → Connectors.
- 2Click “Add custom connector” and paste the connector link above as the remote MCP server URL.
- 3Click Add and start a new chat — Codon Optimization Service capabilities are ready to use.
{
"mcpServers": {
"codon-usage-optimization-mcp": {
"url": "https://edge.vinkius.com/vk_preview_EwhIYVMAwkqiTjDiRdWlLHasxz10yWoao2pKz7gf/mcp"
}
}
}
Claude
ChatGPT
Cursor
VS Code
Windsurf
Claude Code
JetBrains
Cline
Step-by-step instructions for each client are in the guide. How to connect
Guided setup for Claude? Set up Codon Optimization Service in Claude and other AIs
Who it's for
Built for the work Codon Optimization Service owners hand off.
This MCP is designed for professionals working in synthetic biology and genetic engineering who need to automate sequence design.
- 01
Synthetic Biologists
They hand off protein sequences to the AI to get optimized DNA for expression.
- 02
Genetic Engineers
They use the agent to validate host compatibility and sequence complexity.
- 03
Bioinformatics Researchers
They use the capabilities to profile codon usage and structural properties.
FAQ
Questions Codon Optimization Service owners ask.
- 01
What hosts can I optimize sequences for?
The MCP supports optimization for hosts like E. coli and H. sapiens.
- 02
Can I use this with Claude or Cursor?
Yes, you can connect this MCP to any MCP-compatible client including Claude, Cursor, and Windsurf.
- 03
How does it handle protein to DNA conversion?
The optimize_sequence capability takes a protein sequence and generates a DNA sequence tailored to the specific host's codon usage.
- 04
Does it predict translation success?
Yes, the validate_host_compatibility capability predicts if a protein is likely to be compatible with a host's translation machinery.
- 05
Where is the MCP hosted?
Vinkius hosts and manages the MCP, so you don't need to run it locally.
- 06
How does the optimization process work?
The server uses codon usage bias data to select synonymous codons that maximize the Codon Adaptation Index (CAI) for your chosen host.
- 07
Can I avoid specific restriction sites?
Yes, when using optimize_sequence, you can set the avoidRestrictionSites parameter to true to minimize common enzyme recognition sites.
- 08
What hosts are supported?
The server supports a wide range of hosts including E. coli, S. cerevisiae, and H. sapiens.
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Connect Codon Optimization Service to Claude, Cursor, ChatGPT & more
