
Connect Retrosynthetic Analysis Engine to ChatGPT and Claude
Set it up once and it works in ChatGPT, Claude, Cursor, and any other client you love. It all runs safely in the background, so you can relax and focus on what really matters. Map complex molecular pathways from target to precursors.
Developed, maintained, and hosted by Vinkius.
MCP VERIFIED · PRODUCTION READY · VINKIUS GUARANTEED
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Works with modern AI clients that support MCP, including ChatGPT, Claude, Cursor, and more.
Your AI does the work. We keep it safe and sound.
No other AI tool gives you this. Your workflow runs in the client you already love, your account stays protected, and you decide what the agent can and cannot do. It is the whole reason to make the switch.
Each Connector lives inside our infrastructure, the same place where your workflow runs. The three things below are already part of it, working quietly in the background so you never have to think about them. Nothing to add, nothing to set up, nothing to worry about.

Each Connector runs inside its own sealed environment.
Each Connector runs inside its own sealed V8 runtime — no access to your files, your system, or other servers. A Connector never sees past its own request.
One switch stops every agent. Instantly.
One action deactivates every Connector, revokes every token, and ends every session at once. AI Governance keeps the record.
Spending limits that pause instead of surprise.
Every user keeps their own connections and credentials, isolated from everyone else. Anything that would cross your spending limit is held for your approval, not billed.
Three controls, built into the layer your AI connects through.
Curated set · 4 capabilities
We ship only the actions that matter.
01-04
4 capabilities in this set.
Part of 4 available through Retrosynthetic Analysis Engine.
- 01
Generate route tree
This capability builds a complete hierarchical map of synthetic pathways from the target molecule down to available precursors.
- 02
Map synthetic equivalents
This capability suggests real-world chemical reagents that act as the functional equivalents for theoretical synthons.
- 03
Analyze disconnections
This capability finds the most logical points to break a target molecule to simplify its structure.
- 04
Identify synthons
This capability converts strategic bond breaks into theoretical chemical fragments.
Real work
What teams actually run
Target Molecule Deconstruction
Break down a complex structure into simpler, manageable pieces.
Reagent Selection
Find the specific chemicals needed to represent theoretical synthons.
Route Planning
Generate a full map of steps required to synthesize a specific molecule.
Complexity Reduction
Analyze which bond breaks most effectively simplify a target structure.
One connector, every AI
Retrosynthetic Analysis Engine works with the most popular AI clients.
These are the most popular clients, each with a step-by-step guide: one link, set up once, with governance and visibility built in. And because everything runs on the MCP standard, the same connection also works in any other compatible client — nothing to rebuild.
Claude
ChatGPT
Gemini
Perplexity
Grok
Microsoft Copilot
Cursor
VS Code
Windsurf
JetBrains
Cline
LangChain
Vercel AI SDK
Lovable
Z.ai
Raycast
Qwen Code
Kimi Code
Le ChatBuilding your own app? The connector is yours to use.
You don't need a client to put Retrosynthetic Analysis Engine to work: the same hosted connection plugs into your own applications and agent code, with the same governance on every request. Build with it, chat with it — one connection for both.
Observed, not estimated
890ms average. Fast in production.
Retrosynthetic Analysis Engine is checked daily against the live service.
- Fastest day
- 694ms
- Slowest day
- 1128ms
- 14-day trend
- Slowing+15%
Connect your client
One URL. Every client.
Activate the Connector, copy your link, and paste it into the client you already use. 4 capabilities arrive ready to run.
Preview access · not provider authentication
The vk_preview_* token belongs to Vinkius preview infrastructure. It lets Claude discover and display the capabilities of Retrosynthetic Analysis Engine, so you can see the experience inside your AI.
It does not authenticate your account with Retrosynthetic Analysis Engine. Actions requiring credentials or live account data may not run until you activate the Connector and authorize the service.
Retrosynthetic Analysis Engine Connector
You're all set. Choose your MCP client and follow the setup instructions.
https://edge.vinkius.com/vk_preview_eIGNic9jV5heOFVPtGoQTEj3SXdIBltdE2zgL7KI/mcpClaude Desktop
Follow the steps below to connect in seconds.
- 1In Claude Desktop, open Settings → Connectors.
- 2Click “Add custom connector” and paste the connector link above as the remote MCP server URL.
- 3Click Add and start a new chat — Retrosynthetic Analysis Engine capabilities are ready to use.
{
"mcpServers": {
"retrosynthetic-analysis-engine-mcp": {
"url": "https://edge.vinkius.com/vk_preview_eIGNic9jV5heOFVPtGoQTEj3SXdIBltdE2zgL7KI/mcp"
}
}
}
Claude
ChatGPT
Cursor
VS Code
Windsurf
Claude Code
JetBrains
Cline
Step-by-step instructions for each client are in the guide. How to connect
Guided setup for Claude? Set up Retrosynthetic Analysis Engine in Claude and other AIs
Who it's for
Built for the work Retrosynthetic Analysis Engine owners hand off.
This MCP is built for professionals working in organic synthesis and molecular design.
- 01
Medicinal Chemists
Use the agent to quickly brainstorm synthetic routes for new drug candidates.
- 02
Process Chemists
Hand off the initial pathway mapping to the AI to find efficient routes.
- 03
Computational Chemists
Integrate these capabilities into automated molecular design workflows.
FAQ
Questions Retrosynthetic Analysis Engine owners ask.
- 01
What AI clients can I use with this MCP?
You can use this MCP with any compatible client like Claude, Cursor, Windsurf, or VS Code.
- 02
Do I need to host the MCP myself?
No, Vinkius hosts and manages the MCP for you. You just connect your client and start working.
- 03
Can this MCP suggest actual chemicals I can buy?
Yes, the map_synthetic_equivalents capability suggests real-world chemical reagents that perform the function of theoretical synthons.
- 04
How does it handle complex molecules?
It uses analyze_disconnections to find the most logical points to break the molecule to simplify its structure.
- 05
Is this for theoretical chemistry or practical lab work?
It bridges both by converting theoretical fragments into real-world synthetic equivalents.
- 06
What kind of molecular structures can I analyze?
You can analyze molecules provided in SMILES or IUPAC format using the analyze_disconnections capability.
- 07
How does the capability suggest reagents?
The map_synthetic_equivalents capability maps theoretical synthons to stable, commercially available chemical reagents.
- 08
Can I see the full synthesis pathway?
Yes, the generate_route_tree capability constructs a hierarchical map of pathways from the target to starting materials.
Explore
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Connect Retrosynthetic Analysis Engine to Claude, Cursor, ChatGPT & more
