Use CRISPR Guide Designer with your AI.
Connect your account once and let the AI you already use work with it, without building another integration. Design optimal CRISPR guide RNAs by analyzing PAM sites, efficiency, and off-target risks.
Developed, maintained, and hosted by Vinkius.
MCP VERIFIED · PRODUCTION READY · VINKIUS GUARANTEED
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Works with modern AI clients that support MCP, including ChatGPT, Claude, Cursor, and more.
Complete set · 4 capabilities
The complete CRISPR Guide Designer capability set.
These are the exact actions your AI can choose when you ask it to work with CRISPR Guide Designer.
01-04
4 capabilities in this set.
Part of 4 available through CRISPR Guide Designer.
- 01
Assess off target risk
Predicts the danger of unintended cleavage by searching the genome for similar sequences
- 02
Design grna sequences
Generates candidate guide RNA sequences based on identified target locations and PAM sites
- 03
Evaluate on target efficiency
Calculates the predicted effectiveness of specific guide sequences at their intended target
- 04
Find pam sites
G., "NGG"). Identifies all valid locations within a target gene where a PAM sequence exists to allow Cas9 binding
Observed, not estimated
831ms average. Fast in production.
CRISPR Guide Designer is checked daily against the live service.
- Fastest day
- 708ms
- Slowest day
- 882ms
- 14-day trend
- Slowing+9%
Connect your client
One URL. Every client.
Activate the Connector, copy your link, and paste it into the client you already use. 4 capabilities arrive ready to run.
Preview access · not provider authentication
The vk_preview_* token belongs to Vinkius preview infrastructure. It lets Claude discover and display the capabilities of CRISPR Guide Designer, so you can see the experience inside your AI.
It does not authenticate your account with CRISPR Guide Designer. Actions requiring credentials or live account data may not run until you activate the Connector and authorize the service.
CRISPR Guide Designer Connector
You're all set. Choose your MCP client and follow the setup instructions.
https://edge.vinkius.com/vk_preview_VlGBGtl1tMVsdOTySGobGcVYXHeyJJjUv3y6m1sK/mcpClaude Desktop
Follow the steps below to connect in seconds.
- 1In Claude Desktop, open Settings → Connectors.
- 2Click “Add custom connector” and paste the connector link above as the remote MCP server URL.
- 3Click Add and start a new chat — CRISPR Guide Designer capabilities are ready to use.
{
"mcpServers": {
"crispr-guide-designer-mcp": {
"url": "https://edge.vinkius.com/vk_preview_VlGBGtl1tMVsdOTySGobGcVYXHeyJJjUv3y6m1sK/mcp"
}
}
}
Claude
ChatGPT
Cursor
VS Code
Windsurf
Claude Code
JetBrains
Cline
Step-by-step instructions for each client are in the guide. How to connect
FAQ
Questions CRISPR Guide Designer owners ask.
- 01
How do I identify valid target locations?
You can use the find_pam_sites capability by providing the target DNA sequence and the required PAM motif, such as NGG.
- 02
Can I check for off-target risks?
Yes, the assess_off_target_risk capability predicts the danger of unintended cleavage by searching the provided genome reference for similar sequences.
- 03
How is guide efficiency calculated?
The evaluate_on_target_efficiency capability calculates scores based on nucleotide composition and the position of nucleotides relative to the PAM.
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