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Connect CRISPR Guide Designer to ChatGPT, Claude and Gemini

Set it up once and it works in ChatGPT, Claude, Cursor, and any other client you love. It all runs safely in the background, so you can relax and focus on what really matters. Design precise guide RNAs with automated risk assessment.

Ask AI about this Connector

Developed, maintained, and hosted by Vinkius.

MCP VERIFIED · PRODUCTION READY · VINKIUS GUARANTEED

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Works with modern AI clients that support MCP, including ChatGPT, Claude, Cursor, and more.

ChatGPTClaudeCursorPerplexityGeminiMicrosoft CopilotRaycastMeta AI

Your AI does the work. We keep it safe and sound.

No other AI tool gives you this. Your workflow runs in the client you already love, your account stays protected, and you decide what the agent can and cannot do. It is the whole reason to make the switch.

Each Connector lives inside our infrastructure, the same place where your workflow runs. The three things below are already part of it, working quietly in the background so you never have to think about them. Nothing to add, nothing to set up, nothing to worry about.

A futuristic MCP client docking bay
V8 Isolate01

Each Connector runs inside its own sealed environment.

Each Connector runs inside its own sealed V8 runtime — no access to your files, your system, or other servers. A Connector never sees past its own request.

Kill Switch02

One switch stops every agent. Instantly.

One action deactivates every Connector, revokes every token, and ends every session at once. AI Governance keeps the record.

FinOps per User03

Spending limits that pause instead of surprise.

Every user keeps their own connections and credentials, isolated from everyone else. Anything that would cross your spending limit is held for your approval, not billed.

Three controls, built into the layer your AI connects through.

Curated set · 4 capabilities

We ship only the actions that matter.

Capability set01 / 01

01-04

4 capabilities in this set.

Part of 4 available through CRISPR Guide Designer.

  1. 01

    Evaluate on target efficiency

    This capability calculates how effective a specific guide sequence will be at its intended target.

  2. 02

    Design grna sequences

    It generates candidate guide RNA sequences based on your identified target locations and PAM sites.

  3. 03

    Find pam sites

    It identifies all valid locations within a target gene where a PAM sequence exists to allow Cas9 binding.

  4. 04

    Assess off target risk

    This capability predicts the danger of unintended cleavage by searching the genome for similar sequences.

Real work

What teams actually run

01

Rapid Guide Selection

You can quickly generate a list of potential guides for a new gene target and rank them by efficiency.

02

Off-target Screening

Before ordering guides, you can use the agent to check for potential unintended cleavage sites in the genome.

03

Automated Design Pipelines

You can instruct your agent to find all valid NGG sites in a sequence and design guides for each.

04

Experimental Optimization

Use the efficiency capability to compare different guide candidates for the same target site.

One connector, every AI

CRISPR Guide Designer works with the most popular AI clients.

These are the most popular clients, each with a step-by-step guide: one link, set up once, with governance and visibility built in. And because everything runs on the MCP standard, the same connection also works in any other compatible client — nothing to rebuild.

ClaudeClaudeChatGPTChatGPTGeminiGeminiPerplexityPerplexityGrokGrokMicrosoft CopilotMicrosoft CopilotCursorCursorVS CodeVS CodeWindsurfWindsurfJetBrainsJetBrainsClineClineLangChainLangChainVercel AI SDKVercel AI SDKLovableLovableZ.aiZ.aiRaycastRaycastQwen CodeQwen CodeKimi CodeKimi CodeLe ChatLe Chat

Building your own app? The connector is yours to use.

You don't need a client to put CRISPR Guide Designer to work: the same hosted connection plugs into your own applications and agent code, with the same governance on every request. Build with it, chat with it — one connection for both.

Observed, not estimated

963ms average. Fast in production.

CRISPR Guide Designer is checked daily against the live service.

Daily averagePeak 1047ms
Oct 14Today
Fastest day
783ms
Slowest day
1047ms
14-day trend
Slowing+14%

Connect your client

One URL. Every client.

Activate the Connector, copy your link, and paste it into the client you already use. 4 capabilities arrive ready to run.

Preview access · not provider authentication

The vk_preview_* token belongs to Vinkius preview infrastructure. It lets Claude discover and display the capabilities of CRISPR Guide Designer, so you can see the experience inside your AI.

It does not authenticate your account with CRISPR Guide Designer. Actions requiring credentials or live account data may not run until you activate the Connector and authorize the service.

CRISPR Guide Designer Connector

You're all set. Choose your MCP client and follow the setup instructions.

Connector linkhttps://edge.vinkius.com/vk_preview_VlGBGtl1tMVsdOTySGobGcVYXHeyJJjUv3y6m1sK/mcp

Claude Desktop

Follow the steps below to connect in seconds.

  1. 1In Claude Desktop, open Settings → Connectors.
  2. 2Click “Add custom connector” and paste the connector link above as the remote MCP server URL.
  3. 3Click Add and start a new chat — CRISPR Guide Designer capabilities are ready to use.
Configuration · claude_desktop_config.jsonCopy
{
  "mcpServers": {
    "crispr-guide-designer-mcp": {
      "url": "https://edge.vinkius.com/vk_preview_VlGBGtl1tMVsdOTySGobGcVYXHeyJJjUv3y6m1sK/mcp"
    }
  }
}
  • Claude
  • ChatGPT
  • Cursor
  • VS Code
  • Windsurf
  • Claude Code
  • JetBrains
  • Cline

Step-by-step instructions for each client are in the guide. How to connect

Guided setup for Claude? Set up CRISPR Guide Designer in Claude and other AIs

See all the AI clients this connector works with ↑

Who it's for

Built for the work CRISPR Guide Designer owners hand off.

This MCP is built for researchers working in biotechnology and genetics who want to accelerate the guide design process.

  • 01

    Geneticists

    They hand off target sequences to the AI to quickly generate and vet gRNA candidates.

  • 02

    Bioinformaticians

    They use the capability to automate the repetitive tasks of PAM searching and risk assessment.

  • 03

    Lab Researchers

    They use the output to select the most efficient guides for wet lab validation.

FAQ

Questions CRISPR Guide Designer owners ask.

  • 01

    What AI clients can I use with this CRISPR MCP?

    You can use any MCP-compatible client, including Claude, Cursor, Windsurf, and VS Code.

  • 02

    Do I need to host the capabilities myself?

    No, Vinkius hosts and manages the MCP, so it is ready to use immediately after you connect.

  • 03

    Can this MCP help prevent off-target effects?

    Yes, the assess_off_target_risk capability searches the genome for similar sequences to predict unintended cleavage risks.

  • 04

    How does the capability identify PAM sites?

    The find_pam_sites capability scans the target gene to locate valid sequences, such as NGG, required for Cas9 binding.

  • 05

    Is this for Cas9 only?

    The current toolset is specifically designed for CRISPR-Cas9 genome editing design.

  • 06

    How do I identify valid target locations?

    You can use the find_pam_sites capability by providing the target DNA sequence and the required PAM motif, such as NGG.

  • 07

    Can I check for off-target risks?

    Yes, the assess_off_target_risk capability predicts the danger of unintended cleavage by searching the provided genome reference for similar sequences.

  • 08

    How is guide efficiency calculated?

    The evaluate_on_target_efficiency capability calculates scores based on nucleotide composition and the position of nucleotides relative to the PAM.

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