UniProt Connector for AI agents.
3 live capabilities
Access protein sequences and functional data for biological research.
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Why people use UniProt
UniProt Protein Data Search
With this Connector, you just tell your agent what you need. It pulls the sequence, subcellular location, and functional data into your chat in one step. You get the facts you need for your analysis without the manual data entry.
What Vinkius changes
You get instant access to 250 million protein records without needing to manage API keys.
Use it from Claude, ChatGPT, Cursor or another AI client you already have.
One account · 5,900+ Connectors
- Real-world use case 01
Finding a specific protein sequence
A researcher asks for the human p53 sequence.
- Real-world use case 02
Mapping gene isoforms across species
A bioinformatician asks for all proteins encoded by the BRCA1 gene.
- Real-world use case 03
Identifying therapeutic targets
A drug discovery team asks about the ACE2 receptor.
Complete set · 3capabilities
The complete UniProt capability set.
These are the exact actions your AI can choose when you ask it to work with UniProt.
01—03
3 capabilities in this set.
Part of 3 available through UniProt.
- 01 Capability
Search uniprot gene
Find all protein isoforms and functional annotations for a given gene name. Use this to see how a gene is expressed across different types.
- 02 Capability
Get uniprot protein
Get full protein details and sequences using a specific UniProt accession ID. This is useful for pulling exact data for a known protein.
- 03 Capability
Search uniprot
Search the database for proteins by name, function, or keywords like insulin or p53. This helps you find data when you only have a general term.
Set up in minutes
One URL. Then ask UniProt to work.
Claude and ChatGPT only need the Connector URL. Copy it once, add it in settings, and use UniProt from the conversation.
Choose your client
Live previewAdvanced clients IDE · CLI
Claude · Web + desktop
Connector URL · ready to paste
Streamable HTTPhttps://edge.vinkius.com/vk_preview_jPSrejZI835eE2T6bJttqT3k3CdFHVP7joPQheuT/mcp - Step 01
Open Connectors
In Claude Web or Claude Desktop, open Settings and choose Connectors.
- Step 02
Add the URL
Choose Add custom connector, name it UniProt, and paste the URL above.
- Step 03
Turn it on in chat
Select +, open Connectors, and enable UniProt for the conversation.
ChatGPT · Web + desktop
Connector URL · ready to paste
Streamable HTTPhttps://edge.vinkius.com/vk_preview_jPSrejZI835eE2T6bJttqT3k3CdFHVP7joPQheuT/mcp - Step 01
Open MCP settings
On desktop, open Settings and MCP servers. On web, open your workspace app or connector settings.
- Step 02
Add the URL
Choose Add server with Streamable HTTP, or create a custom MCP app, then paste the UniProt URL.
- Step 03
Save and start
Save the connection and enable UniProt in your conversation. Desktop may ask you to restart once.
Cursor · IDE configuration
Advanced setup
{
"mcpServers": {
"uniprot": {
"url": "https://edge.vinkius.com/vk_preview_jPSrejZI835eE2T6bJttqT3k3CdFHVP7joPQheuT/mcp"
}
}
} - Step 01
Open MCP Settings
Press Cmd+Shift+P (macOS) or Ctrl+Shift+P (Windows/Linux) → search "MCP Settings"
- Step 02
Add the server config
Paste the JSON configuration above into the mcp.json file that opens
- Step 03
Save the file
Cursor will automatically detect the new Connector
- Step 04
Start using UniProt
Open Agent mode in chat and ask: "Using UniProt, help me...". 3 tools available
VS Code Copilot · IDE configuration
Advanced setup
{
"mcpServers": {
"uniprot": {
"url": "https://edge.vinkius.com/vk_preview_jPSrejZI835eE2T6bJttqT3k3CdFHVP7joPQheuT/mcp"
}
}
} - Step 01
Create MCP config
Create a .vscode/mcp.json file in your project root
- Step 02
Add the server config
Paste the JSON configuration above
- Step 03
Enable Agent mode
Open GitHub Copilot Chat and switch to Agent mode using the dropdown
- Step 04
Start using UniProt
Ask Copilot: "Using UniProt, help me...". 3 tools available
Windsurf · IDE configuration
Advanced setup
{
"mcpServers": {
"uniprot": {
"url": "https://edge.vinkius.com/vk_preview_jPSrejZI835eE2T6bJttqT3k3CdFHVP7joPQheuT/mcp"
}
}
} - Step 01
Open MCP Settings
Go to Settings → MCP Configuration or press Cmd+Shift+P and search "MCP"
- Step 02
Add the server
Paste the JSON configuration above into mcp_config.json
- Step 03
Save and reload
Windsurf will detect the new server automatically
- Step 04
Start using UniProt
Open Cascade and ask: "Using UniProt, help me...". 3 tools available
Cline · IDE configuration
Advanced setup
{
"mcpServers": {
"uniprot": {
"url": "https://edge.vinkius.com/vk_preview_jPSrejZI835eE2T6bJttqT3k3CdFHVP7joPQheuT/mcp"
}
}
} - Step 01
Open Cline MCP Settings
Click the Connectors icon in the Cline sidebar panel
- Step 02
Add remote server
Click "Add Connector" and paste the configuration above
- Step 03
Enable the server
Toggle the server switch to ON
- Step 04
Start using UniProt
Ask Cline: "Using UniProt, help me...". 3 tools available
Claude Code · Terminal command
Advanced setup
claude mcp add uniprot --transport http "https://edge.vinkius.com/vk_preview_jPSrejZI835eE2T6bJttqT3k3CdFHVP7joPQheuT/mcp" - Step 01
Install Claude Code
Run npm install -g @anthropic-ai/claude-code if not already installed
- Step 02
Add the Connector
Run the command above in your terminal
- Step 03
Verify the connection
Run claude mcp to list connected servers, or type /mcp inside a session
- Step 04
Start using UniProt
Ask Claude: "Using UniProt, show me...". 3 tools are ready
Where the request belongs
Work UniProt can move forward.
Molecular biologists, bioinformaticians, and drug discovery researchers need to find protein sequences and functional data quickly. This Connector removes the friction of manual database navigation, letting them focus on experimental design and target identification.
Molecular Biologist
Look up post-translational modifications and protein domains for experimental design on a Tuesday afternoon.
Bioinformatician
Pull large-scale comparative analyses of protein sequences across multiple species for research papers.
Drug Discovery Researcher
Identify therapeutic targets by pulling disease associations and protein functions into a research pipeline.
Build the capability set
Add more capabilities.
Each Connector adds new actions and data without changing how you work.
Browse ConnectorsEBI Proteins API
Query the UniProt knowledge base for protein sequences, annotations, and functional data across millions of characterized entries.
EBI InterPro
Classify protein sequences into families, predict functional domains, and explore evolutionary relationships across species.
GenBank/NCBI API
Access genomic data. audit sequences, proteins, and UIDs via IA.
Ensembl
Access genomic data, gene trees, homologies, and cross-references from the Ensembl database directly from any AI agent.
KEGG
Access the Kyoto Encyclopedia of Genes and Genomes (KEGG) to query genomic, chemical, and systemic functional information directly from your AI agent.
RCSB PDB
Explore 220K+ 3D molecular structures. search proteins, DNA, and RNA by name, experimental method, resolution, and bound ligands from the Protein Data Bank.
Bring your own AI
Change the model, client or framework. Keep UniProt connected.
-
Claude -
ChatGPT -
Gemini -
Cursor -
VS Code -
Windsurf -
ZCode -
Cline -
Zed -
Continue -
Kiro -
Roo Code -
Zencoder -
Goose -
Void -
Augment Code -
Amp -
Qodo -
Tabnine -
Pieces -
Sourcegraph Cody -
JetBrains -
Warp -
Amazon Q -
Antigravity -
BoltAI -
Raycast -
Jan -
LM Studio -
AnythingLLM -
Open WebUI -
Msty -
Cherry Studio -
LibreChat -
TypingMind -
Chorus -
5ire -
n8n -
LangChain -
LlamaIndex -
CrewAI -
Vercel AI SDK
Before you connect
Questions about UniProt.
The practical details behind the request, access and result.
What is the UniProt MCP?
The UniProt MCP is a capability that lets your AI agent access the world's largest database of protein sequences and functional information. It allows your agent to perform searches and pull biological data directly into your workspace.
Can I use UniProt MCP to find protein sequences?
Yes, you can pull full amino acid sequences for specific proteins using their accession numbers. This is great for research, comparative analysis, and experimental design.
How does UniProt MCP help with drug discovery?
It helps you identify therapeutic targets by pulling functional annotations and disease associations for specific proteins. You can quickly see what a protein does and where it is located in the cell.
Does UniProt MCP support different species?
Yes, it supports data for many organisms. You can use it to find orthologs and paralogs to see how proteins differ across different species like humans, mice, and rats.
Is an API key required for UniProt MCP?
No, you do not need to manage any API keys. You can start searching and pulling protein data immediately after subscribing to the Connector on Vinkius.
Can UniProt MCP find specific gene isoforms?
Yes, the Connector can find all protein isoforms encoded by a specific gene. This is helpful for understanding how different versions of a protein function in different contexts.
What is the difference between Swiss-Prot and TrEMBL entries?
Swiss-Prot contains 570K+ entries that have been manually reviewed and curated by expert biologists. the gold standard for protein annotation. TrEMBL contains 250M+ entries that are computationally annotated from gene sequences. Swiss-Prot entries are marked as 'reviewed' and are highly reliable; TrEMBL entries are automatically generated and may contain errors.
Do I need to register or pay for an API key?
No. UniProt REST API is completely free and open without any authentication. There are no rate limits for reasonable usage patterns. UniProt is funded by the National Institutes of Health (NIH), European Molecular Biology Laboratory (EMBL), and the Swiss Institute of Bioinformatics (SIB).
Can I retrieve full amino acid sequences for proteins?
Yes. Every protein entry includes the full amino acid sequence with length information. The sequence is returned in standard one-letter amino acid code. For very large proteins (10,000+ residues), the sequence may be truncated in the response but the full accession data is always provided for direct download.
One connection away
Give your agent a direct line to UniProt.
Connect UniProt once. Keep it beside 5,900+ managed Connectors when the next task needs more.
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