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How to Use the EBI InterPro MCP in CrewAI

Deploy a specialized crew of autonomous agents to map protein functions using the EBI InterPro MCP Server for hands-off research.

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Connect EBI InterPro MCP to CrewAI

Create your Vinkius account to connect EBI InterPro to CrewAI and route execution through our secure gateway. The platform manages server hosting, runtime updates, and security layers. Configuration requires no manual server provisioning.

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Autonomous protein research with CrewAI

Assign a dedicated agent to run `search_proteins` and `get_protein_entries` while another agent summarizes the results. CrewAI coordinates these roles, creating a research team that works without your constant input. This setup is perfect for high-throughput analysis. Your agents share memory, so the secondary agent knows exactly what the first one found in the EBI InterPro database.

Evolutionary monitoring with CrewAI

Configure an agent to watch for taxonomic shifts using `get_entry_taxonomy` and `search_taxonomy`. You can set this agent to run on a schedule, alerting you only when specific evolutionary criteria are met. Your agents act as a monitor, constantly polling the data. Because they use the EBI InterPro MCP Server, they stay updated with the latest entries without you needing to write manual scripts.

Structural verification crews in CrewAI

Build a crew where one agent identifies protein families and a second agent validates them against `get_entry_structures`. This hierarchical execution ensures your final reports are based on verified experimental data. By delegating the structural checks to a specific agent, you reduce the risk of false positives. The crew handles the heavy lifting of cross-referencing entries and structures.

Setup guide

Set up EBI InterPro MCP in CrewAI

Prerequisites

  • Python 3.10+ installed
  • crewai package (pip install crewai)
  • Active Vinkius subscription with a valid endpoint token
  1. 1

    Install CrewAI

    Run pip install crewai to install the framework. MCP support is built-in via the mcps parameter.

  2. 2

    Add the MCP URL to your agent

    Pass your Vinkius endpoint directly to the mcps list. Replace [YOUR_TOKEN_HERE] with your token from cloud.vinkius.com. CrewAI handles tool discovery and caching automatically.

  3. 3

    Kick off your crew

    Create a Crew with your agent and tasks. Call crew.kickoff() — the agent will automatically invoke EBI InterPro tools as needed.

crew.py
from crewai import Agent, Task, Crew

agent = Agent(
    role="EBI InterPro Analyst",
    goal="Access and analyze EBI InterPro data via MCP.",
    backstory="Expert analyst with direct EBI InterPro access.",
    mcps=[
        "https://edge.vinkius.com/[YOUR_TOKEN_HERE]/mcp"
    ],
)

task = Task(
    description="List recent EBI InterPro transactions",
    agent=agent,
    expected_output="A summary of recent activity",
)

crew = Crew(agents=[agent], tasks=[task])
result = crew.kickoff()
print(result)

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Every tool your AI connects to, managed from a single screen. One account, complete control.

Common questions about EBI InterPro MCP in CrewAI

You pass the server URL directly to the agent definition. The agents then automatically list and use the EBI InterPro tools based on their assigned roles.
Use the tool filter when initializing the MCP server. This limits your agents to only the tools you want them to have access to during their run.
The server runs in a secure, ephemeral Vinkius sandbox. Your research data is never persisted beyond the duration of your agent's task.
The server manages the connection, but you should structure your agent tasks to avoid flooding the API. Space your agent actions to maintain consistent performance.
They can use shared memory to track findings. However, each session is distinct, so ensure you configure your agent persistence if you need long-term research tracking.

Start using the EBI InterPro MCP today

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