PDBe (Protein Data Bank in Europe) Connector for AI agents.

No, the PDBe API is public, so you can start querying data immediately after connecting it to your AI client.

Yes, the Connector can retrieve specific binding site residues and interactions for various ligands, which is a core use case for drug discovery.

No, it provides structural summaries, metadata, and residue listings rather than the raw coordinate files for simulation.

Yes, you can use the search capability to find entries using descriptions like 'insulin receptor kinase' or specific organism names.

It allows you to map UniProt accessions to specific PDB residue numbers for easier cross-referencing between sequence and 3D data.

Yes, you can pull global quality metrics like R-factors and resolution to see if a structure is reliable for your research.

Yes, it can tell you if a protein functions as a monomer, dimer, or a more complex assembly by pulling quaternary structure data.

No. The PDBe API is completely public and requires no authentication. Enter any placeholder value in the API key field to activate the server immediately.

The PDBe contains over 200,000 experimentally determined 3D structures of proteins, nucleic acids, and complex assemblies. Structures are determined by X-ray crystallography, cryo-electron microscopy (cryo-EM), NMR spectroscopy, and other methods. This includes enzymes, receptors, antibodies, viral proteins, ribosomes, and drug-target complexes.

Yes. Use get_binding_sites to retrieve all annotated ligand binding pockets with their constituent residues. Combine with get_ligand_monomers to identify the small molecules bound in the structure, and get_cofactors for prosthetic groups. This workflow is essential for structure-based drug design and virtual screening target preparation.