How to Use the ClinicalTrials.gov MCP in Vercel AI SDK

Connect Vercel AI SDK to the ClinicalTrials.gov MCP Server and stream active research studies straight into your Next.js frontend.

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Connect ClinicalTrials.gov MCP to Vercel AI SDK

Create your Vinkius account to connect ClinicalTrials.gov to Vercel AI SDK and route execution through our secure gateway. The platform manages server hosting, runtime updates, and security layers. Configuration requires no manual server provisioning.

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Setup ClinicalTrials.gov with Vercel AI SDK

Ask AI about this MCP

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Claude

Perplexity

Stream search results via Vercel AI SDK

Users hate waiting for heavy database queries. You can pipe the `search_clinical_trials` tool directly into your streamText function so patients see study titles appearing the millisecond we get a hit. Your Next.js app renders the drug names and sponsor details live. Nobody stares at a loading spinner wondering if the backend crashed.

Map active enrollments instantly

Finding open studies usually means clicking through outdated registry pages. Trigger `find_recruiting_trials` to pull only the sites currently accepting patients for specific conditions. The MCP Server handles the filtering logic before the data hits your UI. Doctors get a clean list of immediate opportunities without manually sorting through closed phases.

Pull full NCT records on demand

Sometimes a researcher needs the exact inclusion criteria for a specific drug protocol. Pass the identifier to `get_trial_details` and let the agent fetch the complete study schema. We format the raw registry dump into clean JSON that React components can actually digest. Complex endpoint mappings disappear behind a single tool call.

Setup guide

Set up ClinicalTrials.gov MCP in Vercel AI SDK

Prerequisites

Node.js 18+ and a TypeScript project
ai + @modelcontextprotocol/sdk packages
Active Vinkius subscription with a valid endpoint token

1

Install dependencies

Run npm install ai @modelcontextprotocol/sdk plus your preferred model provider (e.g. @ai-sdk/openai).
2

Create the Streamable HTTP transport

Use StreamableHTTPClientTransport with your Vinkius endpoint URL. Replace [YOUR_TOKEN_HERE] with your token from cloud.vinkius.com.
3

Discover and use tools

Call mcpClient.tools() to auto-discover all ClinicalTrials.gov tools. Pass them directly to generateText() or streamText() — no manual schema definitions needed.
4

Works with any model provider

Swap openai("gpt-4o") for any AI SDK provider — Anthropic, Google, Mistral. The MCP tools work identically across all supported models.

index.ts

import { experimental_createMCPClient as createMCPClient } from "ai";
import { StreamableHTTPClientTransport } from "@modelcontextprotocol/sdk/client/streamableHttp";
import { generateText } from "ai";
import { openai } from "@ai-sdk/openai";

const transport = new StreamableHTTPClientTransport(
  new URL("https://edge.vinkius.com/[YOUR_TOKEN_HERE]/mcp")
);

const mcpClient = await createMCPClient({ transport });
const tools = await mcpClient.tools();

const { text } = await generateText({
  model: openai("gpt-4o"),
  tools,
  prompt: "List recent ClinicalTrials.gov transactions",
});

console.log(text);
await mcpClient.close();

Get your connection token →

Independent Platform Disclaimer: Vinkius is an independent platform and is not affiliated with, endorsed by, sponsored by, verified by, or otherwise authorized by ClinicalTrials.gov. All third-party trademarks, logos, and brand names are the property of their respective owners. Their use on this website is strictly for informational purposes to identify service compatibility and interoperability.

Why Choose Vinkius

Vinkius connects your tools to AI with real-time monitoring and automatic cost savings — all from one dashboard.

Connect ClinicalTrials.gov now

Real-time monitoring

Live

visibility into every interaction

Connect your favorite tools to your AI and see exactly what's happening — every request, every response, in real time.

Built-in savings

60%

lower AI costs

Vinkius compresses data between your apps and your AI automatically. Lower bills every month — no configuration required.

Single dashboard

One

place for every integration

Every tool your AI connects to, managed from a single screen. One account, complete control.

Common questions about ClinicalTrials.gov MCP in Vercel AI SDK

Install the @ai-sdk/mcp package and set up an HTTP transport pointing to your Vinkius endpoint. Pass the resulting tools to your text generation function. The SDK handles the rest.

Yes. The search tool accepts phase and recruitment status parameters natively. Your prompt dictates the filters, and the MCP protocol executes the exact query.

That is the main advantage of this setup. Tool execution results stream directly to the client as they resolve. Your UI updates while the registry is still processing the full request.

You get structured text or JSON depending on your schema definitions. The raw registry data gets parsed into standard fields like sponsor, phase, and criteria.

The Vinkius V8 Isolate Sandbox executes your queries ephemerally. We only process medical condition keywords and NCT identifiers, leaving zero trace of your users' search history after the session closes.

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