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Why use ClinicalTrials.gov MCP Server with Mastra AI?

Bring Clinical Trials
to Mastra AI

Create your Vinkius account to connect ClinicalTrials.gov to Mastra AI and start using all 3 AI tools in minutes. Fully managed, enterprise secure, and ready to use without writing a single line of code. No hosting, no server setup — just connect and start using.

MCP Inspector GDPR Free for Subscribers
Find Recruiting TrialsGet Trial DetailsSearch Clinical Trials
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Compatible with every major AI agent and IDE

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ClinicalTrials.gov

What is the ClinicalTrials.gov MCP Server?

The ClinicalTrials.gov MCP Server connects your AI agent to the United States National Institutes of Health (NIH) clinical research database — the gold standard for clinical trial transparency worldwide.

Core Capabilities

  • Universal Trial Search — Query over 500,000 registered studies by condition, drug name, sponsor, or any keyword. Filter by recruitment status and trial phase to pinpoint exactly what matters.
  • Deep Trial Profiles — Retrieve full study protocols including eligibility criteria, enrollment targets, intervention details, and sponsor information for any registered trial.
  • Active Recruitment Finder — Dedicated tool for patients and clinicians to discover trials actively enrolling participants right now, searchable by medical condition.

Zero authentication required. Fully open public data maintained by the National Library of Medicine. Critical for pharmaceutical researchers, healthcare professionals, patient advocates, and biotech analysts.

Built-in capabilities (3)

find_recruiting_trials

Useful for patients and healthcare providers looking for active enrollment opportunities. Find clinical trials that are actively recruiting participants for a specific medical condition

get_trial_details

Retrieve full details of a specific clinical trial by its NCT identifier

search_clinical_trials

Can filter by recruitment status and trial phase. Search the ClinicalTrials.gov database for studies by keyword, condition, drug name, or sponsor

Why Mastra AI?

Mastra's agent abstraction provides a clean separation between LLM logic and ClinicalTrials.gov tool infrastructure. Connect 3 tools through Vinkius and use Mastra's built-in workflow engine to chain tool calls with conditional logic, retries, and parallel execution. deployable to any Node.js host in one command.

  • Mastra's agent abstraction provides a clean separation between LLM logic and tool infrastructure. add ClinicalTrials.gov without touching business code

  • Built-in workflow engine chains MCP tool calls with conditional logic, retries, and parallel execution for complex automation

  • TypeScript-native: full type inference for every ClinicalTrials.gov tool response with IDE autocomplete and compile-time checks

  • One-command deployment to any Node.js host. Vercel, Railway, Fly.io, or your own infrastructure

M
See it in action

ClinicalTrials.gov in Mastra AI

AI AgentVinkius
High Security·Kill Switch·Plug and Play
Enterprise Security

Why run ClinicalTrials.gov with Vinkius?

The ClinicalTrials.gov connection runs on our fully managed, secure cloud infrastructure. We handle the hosting, maintenance, and security so you don't have to deal with servers or code. All 3 tools are ready to work instantly without any complex setup.

You stay in complete control of your data. Your AI only accesses the information you approve, keeping your sensitive passwords and private details completely safe. Plus, with automatic optimizations, your AI works faster and more efficiently.

ClinicalTrials.gov
Fully ManagedNo server setup
Plug & PlayNo coding needed
SecurePrivacy protected
PrivateYour data is safe
Cost ControlBudget limits
Control1-click disconnect
Auto-UpdatesMaintenance free
High SpeedOptimized for AI
Reliable99.9% uptime
Your credentials and connection tokens are fully encrypted

* Every connection is hosted and maintained by Vinkius. We handle the security, updates, and infrastructure so you don't have to write code or manage servers. See our infrastructure

01 / Catalog

Over 4,000 integrations ready for AI agents

Explore a vast library of pre-built integrations, optimized and ready to deploy.

02 / Credentials

Connect securely in under 30 seconds

Generate tokens to authenticate and link external services in a single step.

03 / Guardian

Complete visibility into every agent action

Audit live requests, latency, success rates, and active security compliance policies.

04 / FinOps

Optimize spending and track token ROI

Analyze real-time token consumption and cost metrics detailed by connection.

Over 4,000 integrations ready for AI agents
Connect securely in under 30 seconds
Complete visibility into every agent action
Optimize spending and track token ROI

Explore our live AI Agents Analytics dashboard to see it all working

This dashboard is included when you connect ClinicalTrials.gov using Vinkius. You will never be left in the dark about what your AI agents are doing with your tools.

Why Vinkius

ClinicalTrials.gov and 4,000+ other AI tools. No hosting, no code, ready to use.

Professionals who connect ClinicalTrials.gov to Mastra AI through Vinkius don't need to write code, manage servers, or worry about security. Everything is pre-configured, secure, and runs automatically in the background.

4,000+MCP Integrations
<40msResponse time
100%Fully managed
Raw MCP
Vinkius
Ready-to-use MCPsFind and configure each manually4,000+ MCPs ready to use
Connection SetupManual coding & server setup1-click instant connection
Server HostingYou host it yourself (needs 24/7 uptime)100% hosted & managed by Vinkius
Security & PrivacyStored in plaintext config filesBank-grade encrypted vault
Activity VisibilityBlind execution (no logs or tracking)Live dashboard with real-time logs
Cost ControlRunaway AI token spend riskAutomatic budget limits
Revoking AccessMust delete files or code to stop1-click disconnect button
The Vinkius Advantage

How Vinkius secures ClinicalTrials.gov for Mastra AI

Every request between Mastra AI and ClinicalTrials.gov is protected by our secure gateway. We automatically keep your sensitive data private, prevent unauthorized access, and let you disconnect instantly at any time.

< 40msCold start
Ed25519Signed audit chain
60%Token savings
FAQ

Frequently asked questions

01

Do I need an API Key or registration?

No. ClinicalTrials.gov is a fully public service maintained by the US National Library of Medicine. All data is accessible without any authentication.

02

What types of studies can I search for?

The database covers interventional trials (testing drugs, devices, procedures), observational studies, and expanded access programs. You can search across all phases, from early Phase 1 research to post-market Phase 4 surveillance.

03

Is the trial recruiting status updated in real time?

The data reflects what is currently published on the ClinicalTrials.gov database. Sponsors typically update the registry directly, so you will see the latest status logged in their system.

04

How does Mastra AI connect to MCP servers?

Create an MCPClient with the server URL and pass it to your agent. Mastra discovers all tools and makes them available with full TypeScript types.

05

Can Mastra agents use tools from multiple servers?

Yes. Pass multiple MCP clients to the agent constructor. Mastra merges all tool schemas and the agent can call any tool from any server.

06

Does Mastra support workflow orchestration?

Yes. Mastra has a built-in workflow engine that lets you chain MCP tool calls with branching logic, error handling, and parallel execution.

07

createMCPClient not exported

Install: npm install @mastra/mcp

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