Bring Clinical Trials
to Claude Desktop
Create your Vinkius account to connect ClinicalTrials.gov to Claude Desktop and start using all 3 AI tools in minutes. Fully managed, enterprise secure, and ready to use without writing a single line of code. No hosting, no server setup — just connect and start using.
Compatible with every major AI agent and IDE
What is the ClinicalTrials.gov MCP Server?
The ClinicalTrials.gov MCP Server connects your AI agent to the United States National Institutes of Health (NIH) clinical research database — the gold standard for clinical trial transparency worldwide.
Core Capabilities
- Universal Trial Search — Query over 500,000 registered studies by condition, drug name, sponsor, or any keyword. Filter by recruitment status and trial phase to pinpoint exactly what matters.
- Deep Trial Profiles — Retrieve full study protocols including eligibility criteria, enrollment targets, intervention details, and sponsor information for any registered trial.
- Active Recruitment Finder — Dedicated tool for patients and clinicians to discover trials actively enrolling participants right now, searchable by medical condition.
Zero authentication required. Fully open public data maintained by the National Library of Medicine. Critical for pharmaceutical researchers, healthcare professionals, patient advocates, and biotech analysts.
Built-in capabilities (3)
Useful for patients and healthcare providers looking for active enrollment opportunities. Find clinical trials that are actively recruiting participants for a specific medical condition
Retrieve full details of a specific clinical trial by its NCT identifier
Can filter by recruitment status and trial phase. Search the ClinicalTrials.gov database for studies by keyword, condition, drug name, or sponsor
Why Claude Desktop?
Claude Desktop is the definitive way to connect ClinicalTrials.gov to your AI workflow. Add Vinkius Edge URL to your config, restart the app, and Claude immediately exposes all 3 tools in the chat interface. ask a question, Claude calls the right tool, and you see the answer. Zero code, zero context switching.
- —
Claude Desktop is the reference MCP client. it was designed alongside the protocol itself, ensuring the most complete and stable MCP implementation available
- —
Zero-code configuration: add a server URL to a JSON file and Claude instantly discovers and exposes all available tools in the chat interface
- —
Claude's extended thinking capability lets it reason through multi-step tool usage, chaining multiple API calls to answer complex questions
- —
Enterprise-grade security with local config storage. your tokens never leave your machine, and connections go directly to Vinkius Edge network
ClinicalTrials.gov in Claude Desktop
Why run ClinicalTrials.gov with Vinkius?
The ClinicalTrials.gov connection runs on our fully managed, secure cloud infrastructure. We handle the hosting, maintenance, and security so you don't have to deal with servers or code. All 3 tools are ready to work instantly without any complex setup.
You stay in complete control of your data. Your AI only accesses the information you approve, keeping your sensitive passwords and private details completely safe. Plus, with automatic optimizations, your AI works faster and more efficiently.

* Every connection is hosted and maintained by Vinkius. We handle the security, updates, and infrastructure so you don't have to write code or manage servers. See our infrastructure
Over 4,000 integrations ready for AI agents
Explore a vast library of pre-built integrations, optimized and ready to deploy.
Connect securely in under 30 seconds
Generate tokens to authenticate and link external services in a single step.
Complete visibility into every agent action
Audit live requests, latency, success rates, and active security compliance policies.
Optimize spending and track token ROI
Analyze real-time token consumption and cost metrics detailed by connection.




Explore our live AI Agents Analytics dashboard to see it all working
This dashboard is included when you connect ClinicalTrials.gov using Vinkius. You will never be left in the dark about what your AI agents are doing with your tools.
ClinicalTrials.gov and 4,000+ other AI tools. No hosting, no code, ready to use.
Professionals who connect ClinicalTrials.gov to Claude Desktop through Vinkius don't need to write code, manage servers, or worry about security. Everything is pre-configured, secure, and runs automatically in the background.
Raw MCP | Vinkius | |
|---|---|---|
| Ready-to-use MCPs | Find and configure each manually | 4,000+ MCPs ready to use |
| Connection Setup | Manual coding & server setup | 1-click instant connection |
| Server Hosting | You host it yourself (needs 24/7 uptime) | 100% hosted & managed by Vinkius |
| Security & Privacy | Stored in plaintext config files | Bank-grade encrypted vault |
| Activity Visibility | Blind execution (no logs or tracking) | Live dashboard with real-time logs |
| Cost Control | Runaway AI token spend risk | Automatic budget limits |
| Revoking Access | Must delete files or code to stop | 1-click disconnect button |
How Vinkius secures
ClinicalTrials.gov for Claude Desktop
Every request between Claude Desktop and ClinicalTrials.gov is protected by our secure gateway. We automatically keep your sensitive data private, prevent unauthorized access, and let you disconnect instantly at any time.
Frequently asked questions
Do I need an API Key or registration?
No. ClinicalTrials.gov is a fully public service maintained by the US National Library of Medicine. All data is accessible without any authentication.
What types of studies can I search for?
The database covers interventional trials (testing drugs, devices, procedures), observational studies, and expanded access programs. You can search across all phases, from early Phase 1 research to post-market Phase 4 surveillance.
Is the trial recruiting status updated in real time?
The data reflects what is currently published on the ClinicalTrials.gov database. Sponsors typically update the registry directly, so you will see the latest status logged in their system.
How does Claude Desktop discover MCP tools?
When Claude Desktop starts, it reads the claude_desktop_config.json file and connects to each configured MCP server. It calls the tools/list endpoint to fetch the schema for every available tool, then surfaces them as clickable options in the chat interface via the 🔌 icon.
What happens if the MCP server is temporarily unavailable?
Claude Desktop handles disconnections gracefully. if the server is unreachable at startup, the tools simply won't appear. Once the server becomes available again, restarting Claude Desktop will re-establish the connection. There is no timeout penalty or error loop.
Can I connect multiple MCP servers simultaneously?
Yes. You can add as many servers as you need in the mcpServers section of the config file. Each server appears as a separate tool provider, and Claude can use tools from multiple servers in a single conversation turn.
Is there a limit on the number of tools per server?
Claude Desktop can handle hundreds of tools per server. However, for optimal LLM performance, Vinkius servers are designed to expose focused, well-documented tool sets rather than overwhelming the model with too many options.
Does Claude Desktop support Streamable HTTP transport?
Yes. Claude Desktop supports both SSE (Server-Sent Events) and the newer Streamable HTTP transport that Vinkius uses. Simply provide the server URL. Claude auto-negotiates the transport protocol.
Server not appearing after restart
Ensure the JSON is valid (no trailing commas). Check the file path: ~/Library/Application Support/Claude/claude_desktop_config.json (macOS) or %APPDATA%\\Claude\\ (Windows).
Authentication error
Verify your Vinkius token is correct. Go to cloud.vinkius.com to regenerate it if needed.
Tools not showing in chat
Click the 🔌 icon at the bottom of the chat input. If it shows 0 tools, the server may still be connecting. wait a few seconds.
Explore More MCP Servers
View all →
String
10 toolsEngage mobile app users with targeted push notifications, in-app messages, and behavioral triggers that improve retention.

DefiLlama (DeFi Analytics)
19 toolsAccess comprehensive DeFi data including TVL, token prices, yields, and volumes across multiple chains and protocols.

Chili Piper
8 toolsManage scheduling and lead routing via Chili Piper — track meetings, monitor queues, and manage teams directly from any AI agent.

Avalara (AvaTax)
10 toolsAutomate tax calculation and compliance with Avalara AvaTax — calculate rates and resolve addresses via AI.
