Compatible with every major AI agent and IDE
What is the Harvard ClinicalTrials MCP Server?
Connect to the ClinicalTrials.gov API v2 — the largest database of clinical studies worldwide, maintained by the U.S. National Library of Medicine.
What you can do
- Study Search — Search 400K+ clinical trials from 220+ countries
- Condition Filter — Find trials for specific diseases (cancer, diabetes, Alzheimer's)
- Intervention Filter — Search by drug, device, or therapy name
- Sponsor Search — Find trials by organization (Pfizer, NIH, Roche)
- Phase Filter — Filter by Phase 1-4 to track drug development stages
- Recruiting — Find trials currently enrolling participants
- Location — Search by city or country for accessible trials
- FDA Regulated — Filter for FDA-regulated drug and device trials
- Pediatric — Find trials including children
- Rare Diseases — Discover research for orphan conditions
- Results — Get outcome data from completed studies
Who is this for?
- Medical Researchers — systematic reviews and evidence synthesis
- Clinicians — find trial evidence for treatment decisions
- Patients — discover trials they may be eligible for
- Pharma Professionals — competitive landscape and pipeline analysis
Built-in capabilities (16)
gov API version and the timestamp of the most recent data update. Useful for verifying data currency and API availability. Get API version and data timestamp
g. "NCT04368728"). Returns title, status, phase, enrollment, conditions, interventions, eligibility criteria, sponsor, and study locations. Get clinical trial details by NCT ID
Not all trials report results — this is most useful for completed Phase 2-4 studies. Get primary outcome results for a trial
Essential for understanding the progress and currency of a study. Get the complete timeline of a clinical trial
Examples: "diabetes", "breast cancer", "Alzheimer disease", "COVID-19", "depression", "hypertension". Search trials by medical condition
Examples: "pembrolizumab", "metformin", "radiation therapy", "cognitive behavioral therapy". Search trials by drug or treatment
Essential for finding trials accessible to patients in a particular area. Search trials by geographic location
Phase values: "PHASE1", "PHASE2", "PHASE3", "PHASE4", "EARLY_PHASE1". Phase 3 trials are the largest and most definitive, while Phase 1 trials focus on safety. Search trials by study phase
Examples: "Pfizer", "National Cancer Institute", "Roche", "Novartis", "NIH". Search trials by sponsoring organization
Completed trials are more likely to have published results and outcomes data. Search completed clinical trials
Covers diagnostic devices, surgical tools, implants, and digital health technologies. Search medical device clinical trials
S. Food and Drug Administration. These trials follow the most rigorous regulatory standards. Search FDA-regulated drug trials
Essential for pediatricians, child health researchers, and parents seeking trials for children. Search pediatric clinical trials
Examples: "cystic fibrosis", "sickle cell disease", "Huntington disease", "amyotrophic lateral sclerosis". Search rare disease clinical trials
Essential for patients seeking to enroll in trials or researchers tracking active studies. Search for currently recruiting studies
gov database of over 400,000 clinical studies from 200+ countries. Returns NCT IDs, titles, status, phases, sponsors, conditions, interventions, and locations. Search 400K+ clinical trials worldwide
Why Cline?
Cline operates autonomously inside VS Code. it reads your codebase, plans a strategy, and executes multi-step tasks including Harvard ClinicalTrials tool calls without waiting for prompts between steps. Connect 16 tools through Vinkius and Cline can fetch data, generate code, and commit changes in a single autonomous run.
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Cline operates autonomously. it reads your codebase, plans a strategy, and executes multi-step tasks including MCP tool calls without step-by-step prompts
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Runs inside VS Code, so you get MCP tool access alongside your existing extensions, terminal, and version control in a single window
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Cline can create, edit, and delete files based on MCP tool responses, enabling end-to-end automation from data retrieval to code generation
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Transparent execution: every tool call and file change is shown in Cline's activity log for full visibility and approval before committing
Harvard ClinicalTrials in Cline
Harvard ClinicalTrials and 4,000+ other MCP servers. One platform. One governance layer.
Teams that connect Harvard ClinicalTrials to Cline through Vinkius don't need to source, host, or maintain individual MCP servers. Every tool call runs inside a hardened runtime with credential isolation, DLP, and a signed audit chain.
Raw MCP | Vinkius | |
|---|---|---|
| Server catalog | Find and host yourself | 4,000+ managed |
| Infrastructure | Self-hosted | Sandboxed V8 isolates |
| Credential handling | Plaintext in config | Vault + runtime injection |
| Data loss prevention | None | Configurable DLP policies |
| Kill switch | None | Global instant shutdown |
| Financial circuit breakers | None | Per-server limits + alerts |
| Audit trail | None | Ed25519 signed logs |
| SIEM log streaming | None | Splunk, Datadog, Webhook |
| Honeytokens | None | Canary alerts on leak |
| Custom domains | Not applicable | DNS challenge verified |
| GDPR compliance | Manual effort | Automated purge + export |
Why teams choose Vinkius for Harvard ClinicalTrials in Cline
The Harvard ClinicalTrials MCP Server runs on Vinkius-managed infrastructure inside AWS — a purpose-built runtime with per-request V8 isolates, Ed25519 signed audit chains, and sub-40ms cold starts. All 16 tools execute in hardened sandboxes optimized for native MCP execution.
Your AI agents in Cline only access the data you authorize, with DLP that blocks sensitive information from ever reaching the model, kill switch for instant shutdown, and up to 60% token savings. Enterprise-grade infrastructure, zero maintenance.

* Every MCP server runs on Vinkius-managed infrastructure inside AWS - a purpose-built runtime with per-request V8 isolates, Ed25519 signed audit chains, and sub-40ms cold starts optimized for native MCP execution. See our infrastructure
How Vinkius secures
Harvard ClinicalTrials for Cline
Every tool call from Cline to the Harvard ClinicalTrials MCP Server is protected by DLP redaction, cryptographic audit chains, V8 sandbox isolation, kill switch, and financial circuit breakers.
Frequently asked questions
Do I need an API key?
No. ClinicalTrials.gov is completely free and public. No authentication required.
What are clinical trial phases?
Phase 1 tests safety in small groups; Phase 2 evaluates efficacy; Phase 3 confirms effectiveness in large populations; Phase 4 monitors post-approval. Each phase provides progressively stronger evidence.
Can patients find trials to enroll in?
Yes. Use the recruiting filter to find trials currently accepting participants. You can filter by condition, location, and eligibility criteria to find accessible trials.
How does Cline connect to MCP servers?
Cline reads MCP server configurations from its settings panel in VS Code. Add the server URL and Cline discovers all available tools on initialization.
Can Cline run MCP tools without approval?
By default, Cline asks for confirmation before executing tool calls. You can configure auto-approval rules for trusted servers in the settings.
Does Cline support multiple MCP servers at once?
Yes. Configure as many servers as needed. Cline can use tools from different servers within the same autonomous task execution.
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