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OpenAI Agents SDKSDK
OpenAI Agents SDK
Harvard ClinicalTrials MCP Server

Bring Clinical Trials
to OpenAI Agents SDK

Learn how to connect Harvard ClinicalTrials to OpenAI Agents SDK and start using 16 AI agent tools in minutes. Fully managed, enterprise secure, and ready to use without writing a single line of code.

MCP Inspector GDPR Free for Subscribers
Get Api VersionGet StudyGet Study ResultsGet Study TimelineSearch By ConditionSearch By InterventionSearch By LocationSearch By PhaseSearch By SponsorSearch CompletedSearch Device TrialsSearch Fda RegulatedSearch PediatricSearch Rare DiseasesSearch RecruitingSearch Studies

Compatible with every major AI agent and IDE

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Harvard ClinicalTrials

What is the Harvard ClinicalTrials MCP Server?

Connect to the ClinicalTrials.gov API v2 — the largest database of clinical studies worldwide, maintained by the U.S. National Library of Medicine.

What you can do

  • Study Search — Search 400K+ clinical trials from 220+ countries
  • Condition Filter — Find trials for specific diseases (cancer, diabetes, Alzheimer's)
  • Intervention Filter — Search by drug, device, or therapy name
  • Sponsor Search — Find trials by organization (Pfizer, NIH, Roche)
  • Phase Filter — Filter by Phase 1-4 to track drug development stages
  • Recruiting — Find trials currently enrolling participants
  • Location — Search by city or country for accessible trials
  • FDA Regulated — Filter for FDA-regulated drug and device trials
  • Pediatric — Find trials including children
  • Rare Diseases — Discover research for orphan conditions
  • Results — Get outcome data from completed studies

Who is this for?

  • Medical Researchers — systematic reviews and evidence synthesis
  • Clinicians — find trial evidence for treatment decisions
  • Patients — discover trials they may be eligible for
  • Pharma Professionals — competitive landscape and pipeline analysis

Built-in capabilities (16)

get_api_version

gov API version and the timestamp of the most recent data update. Useful for verifying data currency and API availability. Get API version and data timestamp

get_study

g. "NCT04368728"). Returns title, status, phase, enrollment, conditions, interventions, eligibility criteria, sponsor, and study locations. Get clinical trial details by NCT ID

get_study_results

Not all trials report results — this is most useful for completed Phase 2-4 studies. Get primary outcome results for a trial

get_study_timeline

Essential for understanding the progress and currency of a study. Get the complete timeline of a clinical trial

search_by_condition

Examples: "diabetes", "breast cancer", "Alzheimer disease", "COVID-19", "depression", "hypertension". Search trials by medical condition

search_by_intervention

Examples: "pembrolizumab", "metformin", "radiation therapy", "cognitive behavioral therapy". Search trials by drug or treatment

search_by_location

Essential for finding trials accessible to patients in a particular area. Search trials by geographic location

search_by_phase

Phase values: "PHASE1", "PHASE2", "PHASE3", "PHASE4", "EARLY_PHASE1". Phase 3 trials are the largest and most definitive, while Phase 1 trials focus on safety. Search trials by study phase

search_by_sponsor

Examples: "Pfizer", "National Cancer Institute", "Roche", "Novartis", "NIH". Search trials by sponsoring organization

search_completed

Completed trials are more likely to have published results and outcomes data. Search completed clinical trials

search_device_trials

Covers diagnostic devices, surgical tools, implants, and digital health technologies. Search medical device clinical trials

search_fda_regulated

S. Food and Drug Administration. These trials follow the most rigorous regulatory standards. Search FDA-regulated drug trials

search_pediatric

Essential for pediatricians, child health researchers, and parents seeking trials for children. Search pediatric clinical trials

search_rare_diseases

Examples: "cystic fibrosis", "sickle cell disease", "Huntington disease", "amyotrophic lateral sclerosis". Search rare disease clinical trials

search_recruiting

Essential for patients seeking to enroll in trials or researchers tracking active studies. Search for currently recruiting studies

search_studies

gov database of over 400,000 clinical studies from 200+ countries. Returns NCT IDs, titles, status, phases, sponsors, conditions, interventions, and locations. Search 400K+ clinical trials worldwide

Why OpenAI Agents SDK?

The OpenAI Agents SDK auto-discovers all 16 tools from Harvard ClinicalTrials through native MCP integration. Build agents with built-in guardrails, tracing, and handoff patterns. chain multiple agents where one queries Harvard ClinicalTrials, another analyzes results, and a third generates reports, all orchestrated through Vinkius.

  • Native MCP integration via MCPServerSse, pass the URL and the SDK auto-discovers all tools with full type safety

  • Built-in guardrails, tracing, and handoff patterns let you build production-grade agents without reinventing safety infrastructure

  • Lightweight and composable: chain multiple agents and MCP servers in a single pipeline with minimal boilerplate

  • First-party OpenAI support ensures optimal compatibility with GPT models for tool calling and structured output

O
See it in action

Harvard ClinicalTrials in OpenAI Agents SDK

AI AgentVinkius
High Security·Kill Switch·Plug and Play
Why Vinkius

Harvard ClinicalTrials and 4,000+ other MCP servers. One platform. One governance layer.

Teams that connect Harvard ClinicalTrials to OpenAI Agents SDK through Vinkius don't need to source, host, or maintain individual MCP servers. Every tool call runs inside a hardened runtime with credential isolation, DLP, and a signed audit chain.

4,000+MCP Servers ready
<40msCold start
60%Token savings
Raw MCP
Vinkius
Server catalogFind and host yourself4,000+ managed
InfrastructureSelf-hostedSandboxed V8 isolates
Credential handlingPlaintext in configVault + runtime injection
Data loss preventionNoneConfigurable DLP policies
Kill switchNoneGlobal instant shutdown
Financial circuit breakersNonePer-server limits + alerts
Audit trailNoneEd25519 signed logs
SIEM log streamingNoneSplunk, Datadog, Webhook
HoneytokensNoneCanary alerts on leak
Custom domainsNot applicableDNS challenge verified
GDPR complianceManual effortAutomated purge + export
Enterprise Security

Why teams choose Vinkius for Harvard ClinicalTrials in OpenAI Agents SDK

The Harvard ClinicalTrials MCP Server runs on Vinkius-managed infrastructure inside AWS — a purpose-built runtime with per-request V8 isolates, Ed25519 signed audit chains, and sub-40ms cold starts. All 16 tools execute in hardened sandboxes optimized for native MCP execution.

Your AI agents in OpenAI Agents SDK only access the data you authorize, with DLP that blocks sensitive information from ever reaching the model, kill switch for instant shutdown, and up to 60% token savings. Enterprise-grade infrastructure, zero maintenance.

Harvard ClinicalTrials
Fully ManagedVinkius Servers
60%Token savings
High SecurityEnterprise-grade
IAMAccess control
EU AI ActCompliant
DLPData protection
V8 IsolateSandboxed
Ed25519Audit chain
<40msKill switch
Stream every event to Splunk, Datadog, or your own webhook in real-time

* Every MCP server runs on Vinkius-managed infrastructure inside AWS - a purpose-built runtime with per-request V8 isolates, Ed25519 signed audit chains, and sub-40ms cold starts optimized for native MCP execution. See our infrastructure

The Vinkius Advantage

How Vinkius secures Harvard ClinicalTrials for OpenAI Agents SDK

Every tool call from OpenAI Agents SDK to the Harvard ClinicalTrials MCP Server is protected by DLP redaction, cryptographic audit chains, V8 sandbox isolation, kill switch, and financial circuit breakers.

< 40msCold start
Ed25519Signed audit chain
60%Token savings
FAQ

Frequently asked questions

01

Do I need an API key?

No. ClinicalTrials.gov is completely free and public. No authentication required.

02

What are clinical trial phases?

Phase 1 tests safety in small groups; Phase 2 evaluates efficacy; Phase 3 confirms effectiveness in large populations; Phase 4 monitors post-approval. Each phase provides progressively stronger evidence.

03

Can patients find trials to enroll in?

Yes. Use the recruiting filter to find trials currently accepting participants. You can filter by condition, location, and eligibility criteria to find accessible trials.

04

How does the OpenAI Agents SDK connect to MCP?

Use MCPServerSse(url=...) to create a server connection. The SDK auto-discovers all tools and makes them available to your agent with full type information.

05

Can I use multiple MCP servers in one agent?

Yes. Pass a list of MCPServerSse instances to the agent constructor. The agent can use tools from all connected servers within a single run.

06

Does the SDK support streaming responses?

Yes. The SDK supports SSE and Streamable HTTP transports, both of which work natively with Vinkius.

07

MCPServerStreamableHttp not found

Ensure you have the latest version: pip install --upgrade openai-agents

08

Agent not calling tools

Make sure your prompt explicitly references the task the tools can help with.

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