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Harvard ClinicalTrials MCP Server for OpenAI Agents SDKGive OpenAI Agents SDK instant access to 16 tools to Get Api Version, Get Study, Get Study Results, and more

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The OpenAI Agents SDK enables production-grade agent workflows in Python. Connect Harvard ClinicalTrials through Vinkius and your agents gain typed, auto-discovered tools with built-in guardrails. no manual schema definitions required.

Ask AI about this MCP Server for OpenAI Agents SDK

The Harvard ClinicalTrials MCP Server for OpenAI Agents SDK is a standout in the Data Analytics category — giving your AI agent 16 tools to work with, ready to go from day one.

Built for AI Agents by Vinkius

Vinkius delivers Streamable HTTP and SSE to any MCP client

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python
import asyncio
from agents import Agent, Runner
from agents.mcp import MCPServerStreamableHttp

async def main():
    # Your Vinkius token. get it at cloud.vinkius.com
    async with MCPServerStreamableHttp(
        url="https://edge.vinkius.com/[YOUR_TOKEN_HERE]/mcp"
    ) as mcp_server:

        agent = Agent(
            name="Harvard ClinicalTrials Assistant",
            instructions=(
                "You help users interact with Harvard ClinicalTrials. "
                "You have access to 16 tools."
            ),
            mcp_servers=[mcp_server],
        )

        result = await Runner.run(
            agent, "List all available tools from Harvard ClinicalTrials"
        )
        print(result.final_output)

asyncio.run(main())
Harvard ClinicalTrials
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About Harvard ClinicalTrials MCP Server

Connect to the ClinicalTrials.gov API v2 — the largest database of clinical studies worldwide, maintained by the U.S. National Library of Medicine.

The OpenAI Agents SDK auto-discovers all 16 tools from Harvard ClinicalTrials through native MCP integration. Build agents with built-in guardrails, tracing, and handoff patterns. chain multiple agents where one queries Harvard ClinicalTrials, another analyzes results, and a third generates reports, all orchestrated through Vinkius.

What you can do

  • Study Search — Search 400K+ clinical trials from 220+ countries
  • Condition Filter — Find trials for specific diseases (cancer, diabetes, Alzheimer's)
  • Intervention Filter — Search by drug, device, or therapy name
  • Sponsor Search — Find trials by organization (Pfizer, NIH, Roche)
  • Phase Filter — Filter by Phase 1-4 to track drug development stages
  • Recruiting — Find trials currently enrolling participants
  • Location — Search by city or country for accessible trials
  • FDA Regulated — Filter for FDA-regulated drug and device trials
  • Pediatric — Find trials including children
  • Rare Diseases — Discover research for orphan conditions
  • Results — Get outcome data from completed studies

The Harvard ClinicalTrials MCP Server exposes 16 tools through the Vinkius. Connect it to OpenAI Agents SDK in under two minutes — credentials fully managed, no infrastructure to provision, no vendor lock-in. Your configuration, your data, your control.

All 16 Harvard ClinicalTrials tools available for OpenAI Agents SDK

When OpenAI Agents SDK connects to Harvard ClinicalTrials through Vinkius, your AI agent gets direct access to every tool listed below — spanning clinical-trials, medical-research, drug-development, and more. Every call runs in a secure, isolated environment with full audit visibility. Beyond a simple connection, you get real-time monitoring of agent activity, enterprise governance, and optimized token usage.

get

Get api version on Harvard ClinicalTrials

gov API version and the timestamp of the most recent data update. Useful for verifying data currency and API availability. Get API version and data timestamp

get

Get study on Harvard ClinicalTrials

g. "NCT04368728"). Returns title, status, phase, enrollment, conditions, interventions, eligibility criteria, sponsor, and study locations. Get clinical trial details by NCT ID

get

Get study results on Harvard ClinicalTrials

Not all trials report results — this is most useful for completed Phase 2-4 studies. Get primary outcome results for a trial

get

Get study timeline on Harvard ClinicalTrials

Essential for understanding the progress and currency of a study. Get the complete timeline of a clinical trial

search

Search by condition on Harvard ClinicalTrials

Examples: "diabetes", "breast cancer", "Alzheimer disease", "COVID-19", "depression", "hypertension". Search trials by medical condition

search

Search by intervention on Harvard ClinicalTrials

Examples: "pembrolizumab", "metformin", "radiation therapy", "cognitive behavioral therapy". Search trials by drug or treatment

search

Search by location on Harvard ClinicalTrials

Essential for finding trials accessible to patients in a particular area. Search trials by geographic location

search

Search by phase on Harvard ClinicalTrials

Phase values: "PHASE1", "PHASE2", "PHASE3", "PHASE4", "EARLY_PHASE1". Phase 3 trials are the largest and most definitive, while Phase 1 trials focus on safety. Search trials by study phase

search

Search by sponsor on Harvard ClinicalTrials

Examples: "Pfizer", "National Cancer Institute", "Roche", "Novartis", "NIH". Search trials by sponsoring organization

search

Search completed on Harvard ClinicalTrials

Completed trials are more likely to have published results and outcomes data. Search completed clinical trials

search

Search device trials on Harvard ClinicalTrials

Covers diagnostic devices, surgical tools, implants, and digital health technologies. Search medical device clinical trials

search

Search fda regulated on Harvard ClinicalTrials

S. Food and Drug Administration. These trials follow the most rigorous regulatory standards. Search FDA-regulated drug trials

search

Search pediatric on Harvard ClinicalTrials

Essential for pediatricians, child health researchers, and parents seeking trials for children. Search pediatric clinical trials

search

Search rare diseases on Harvard ClinicalTrials

Examples: "cystic fibrosis", "sickle cell disease", "Huntington disease", "amyotrophic lateral sclerosis". Search rare disease clinical trials

search

Search recruiting on Harvard ClinicalTrials

Essential for patients seeking to enroll in trials or researchers tracking active studies. Search for currently recruiting studies

search

Search studies on Harvard ClinicalTrials

gov database of over 400,000 clinical studies from 200+ countries. Returns NCT IDs, titles, status, phases, sponsors, conditions, interventions, and locations. Search 400K+ clinical trials worldwide

Connect Harvard ClinicalTrials to OpenAI Agents SDK via MCP

Follow these steps to wire Harvard ClinicalTrials into OpenAI Agents SDK. The entire setup takes under two minutes — your credentials stay safe behind Vinkius.

01

Install the SDK

Run pip install openai-agents in your Python environment
02

Replace the token

Replace [YOUR_TOKEN_HERE] with your Vinkius token from cloud.vinkius.com
03

Run the script

Save the code above and run it: python agent.py
04

Explore tools

The agent will automatically discover 16 tools from Harvard ClinicalTrials

Why Use OpenAI Agents SDK with the Harvard ClinicalTrials MCP Server

OpenAI Agents SDK provides unique advantages when paired with Harvard ClinicalTrials through the Model Context Protocol.

01

Native MCP integration via `MCPServerSse`, pass the URL and the SDK auto-discovers all tools with full type safety

02

Built-in guardrails, tracing, and handoff patterns let you build production-grade agents without reinventing safety infrastructure

03

Lightweight and composable: chain multiple agents and MCP servers in a single pipeline with minimal boilerplate

04

First-party OpenAI support ensures optimal compatibility with GPT models for tool calling and structured output

Harvard ClinicalTrials + OpenAI Agents SDK Use Cases

Practical scenarios where OpenAI Agents SDK combined with the Harvard ClinicalTrials MCP Server delivers measurable value.

01

Automated workflows: build agents that query Harvard ClinicalTrials, process the data, and trigger follow-up actions autonomously

02

Multi-agent orchestration: create specialist agents. one queries Harvard ClinicalTrials, another analyzes results, a third generates reports

03

Data enrichment pipelines: stream data through Harvard ClinicalTrials tools and transform it with OpenAI models in a single async loop

04

Customer support bots: agents query Harvard ClinicalTrials to resolve tickets, look up records, and update statuses without human intervention

Example Prompts for Harvard ClinicalTrials in OpenAI Agents SDK

Ready-to-use prompts you can give your OpenAI Agents SDK agent to start working with Harvard ClinicalTrials immediately.

01

"Find recruiting Phase 3 trials for breast cancer immunotherapy"

02

"Search for Alzheimer's disease trials sponsored by NIH in Boston"

03

"Find pediatric clinical trials for cystic fibrosis"

Troubleshooting Harvard ClinicalTrials MCP Server with OpenAI Agents SDK

Common issues when connecting Harvard ClinicalTrials to OpenAI Agents SDK through Vinkius, and how to resolve them.

01

MCPServerStreamableHttp not found

Ensure you have the latest version: pip install --upgrade openai-agents
02

Agent not calling tools

Make sure your prompt explicitly references the task the tools can help with.

Harvard ClinicalTrials + OpenAI Agents SDK FAQ

Common questions about integrating Harvard ClinicalTrials MCP Server with OpenAI Agents SDK.

01

How does the OpenAI Agents SDK connect to MCP?

Use MCPServerSse(url=...) to create a server connection. The SDK auto-discovers all tools and makes them available to your agent with full type information.
02

Can I use multiple MCP servers in one agent?

Yes. Pass a list of MCPServerSse instances to the agent constructor. The agent can use tools from all connected servers within a single run.
03

Does the SDK support streaming responses?

Yes. The SDK supports SSE and Streamable HTTP transports, both of which work natively with Vinkius.

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