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EBI Proteins API MCP Server for CursorGive Cursor instant access to 16 tools to Get Antigen, Get Coordinates, Get Genecentric, and more

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Cursor is an AI-first code editor built on VS Code that integrates LLM-powered coding assistance directly into the development workflow. Its Agent mode enables autonomous multi-step coding tasks, and MCP support lets agents access external data sources and APIs during code generation.

Ask AI about this MCP Server for Cursor

The EBI Proteins API MCP Server for Cursor is a standout in the The Unthinkable category — giving your AI agent 16 tools to work with, ready to go from day one.

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Classic Setup·json
{
  "mcpServers": {
    "ebi-proteins-api": {
      "url": "https://edge.vinkius.com/[YOUR_TOKEN_HERE]/mcp"
    }
  }
}
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About EBI Proteins API MCP Server

Connect to the EMBL-EBI Proteins API and access comprehensive protein biology data from one of the world's leading bioinformatics institutes.

Cursor's Agent mode turns EBI Proteins API into an in-editor superpower. Ask Cursor to generate code using live data from EBI Proteins API and it fetches, processes, and writes. all in a single agentic loop. 16 tools appear alongside file editing and terminal access, creating a unified development environment grounded in real-time information.

What you can do

  • Protein Retrieval — Fetch complete protein entries by UniProt accession with names, organisms, gene information, sequences, and cross-references
  • Sequence Features — Retrieve annotated domains, binding sites, active sites, signal peptides, transmembrane regions, and disulfide bonds for any protein
  • Genetic Variants — Access curated variants from UniProtKB aggregated with large-scale studies including ClinVar, gnomAD, 1000 Genomes, COSMIC, and TOPMed
  • Proteomics & PTMs — Query mass-spectrometry peptide evidence and post-translational modifications from PeptideAtlas, MaxQB, EPD, and ProteomicsDB
  • Mutagenesis — Explore curated mutagenesis experiments with detailed phenotypic effect descriptions
  • Proteomes & Taxonomy — Search reference proteomes and navigate the taxonomy tree by ID or organism name
  • Genome Coordinates — Map proteins to genome positions on GRCh38/GRCh37 with Ensembl gene, transcript, and translation IDs

The EBI Proteins API MCP Server exposes 16 tools through the Vinkius. Connect it to Cursor in under two minutes — credentials fully managed, no infrastructure to provision, no vendor lock-in. Your configuration, your data, your control.

All 16 EBI Proteins API tools available for Cursor

When Cursor connects to EBI Proteins API through Vinkius, your AI agent gets direct access to every tool listed below — spanning proteins, uniprot, bioinformatics, and more. Every call runs in a secure, isolated environment with full audit visibility. Beyond a simple connection, you get real-time monitoring of agent activity, enterprise governance, and optimized token usage.

get

Get antigen on EBI Proteins API

These are peptide regions used for antibody generation, indicating experimentally validated protein expression targets. Useful for immunology and antibody-based research. Get antigen sequences from Human Protein Atlas

get

Get coordinates on EBI Proteins API

Returns Ensembl gene, transcript, and translation IDs along with chromosome, start/end positions, and strand information. Essential for bridging protein annotations with genomic data. Get genome coordinate mappings for a protein

get

Get genecentric on EBI Proteins API

Shows canonical protein and related protein count for each gene. Use with a UniProt Proteome ID (e.g. UP000005640). Get the gene-centric view of a proteome

get

Get mutagenesis on EBI Proteins API

Each entry includes the wild-type and mutant residues, position, and a description of the functional impact. Critical for understanding structure-function relationships. Get mutagenesis experiments and phenotypic effects

get

Get protein on EBI Proteins API

Use a UniProt accession such as P12345, Q9Y6K9, or P53_HUMAN. Retrieve a full protein entry by UniProt accession

get

Get protein features on EBI Proteins API

Features include domains, binding sites, active sites, signal peptides, transmembrane regions, disulfide bonds, glycosylation sites, and more. Each feature has start/end positions and evidence counts. Get sequence feature annotations for a protein

get

Get proteome on EBI Proteins API

Returns taxonomy, protein count, gene count, reference status, and component information. Use IDs like UP000005640 for human proteome or UP000000589 for mouse. Get a specific proteome by UniProt Proteome ID

get

Get proteomics on EBI Proteins API

Shows which peptides have been experimentally detected and whether they are unique to this protein. Essential for validating protein expression. Get mass-spectrometry proteomics data for a protein

get

Get proteomics ptm on EBI Proteins API

Provides residue-level PTM positions with evidence counts. Get post-translational modifications from mass-spec data

get

Get taxonomy on EBI Proteins API

Returns scientific name, common name, rank, lineage, parent, and children nodes. Use IDs like 9606 for human, 10090 for mouse, 562 for E. coli. Get taxonomy node details by NCBI taxon ID

get

Get variation on EBI Proteins API

Each variant includes wild-type and mutant residues, clinical significance, consequence type (e.g. missense, nonsense), and cross-references. Critical for clinical genomics and variant interpretation. Get genetic variants for a protein from multiple sources

search

Search features by type on EBI Proteins API

Valid types include: DOMAIN, BINDING, ACTIVE_SITE, SIGNAL, TRANSMEM, DISULFID, CARBOHYD, MOD_RES, VARIANT, MUTAGEN, REGION, MOTIF, SITE, REPEAT, COILED, COMPBIAS, HELIX, STRAND, TURN. Search features by type across proteins

search

Search proteins on EBI Proteins API

You can combine gene name (e.g. TP53), organism (e.g. human, 9606), keyword (e.g. kinase), or accession. Returns a summarized list of matching proteins with names, organisms, and sequence lengths. Search proteins by gene name, organism, or keyword

search

Search proteomes on EBI Proteins API

Returns proteome IDs, taxonomy, protein counts, gene counts, and reference proteome status. Use queries like "homo sapiens", "escherichia coli", "arabidopsis". Search proteomes by organism name

search

Search taxonomy on EBI Proteins API

Returns matching taxonomy entries with scientific names, common names, taxon IDs, and ranks. Useful for finding the correct taxon ID before querying proteins or proteomes for a specific organism. Search taxonomy by organism name

search

Search variation on EBI Proteins API

g. large_scale_study, uniprot, mixed), consequence type (e.g. missense, stop gained), and wild-type residue. Use this to find clinically relevant variants across the proteome. Search variants by consequence type, source, or residue

Connect EBI Proteins API to Cursor via MCP

Follow these steps to wire EBI Proteins API into Cursor. The entire setup takes under two minutes — your credentials stay safe behind Vinkius.

01

Open MCP Settings

Press Cmd+Shift+P (macOS) or Ctrl+Shift+P (Windows/Linux) → search "MCP Settings"
02

Add the server config

Paste the JSON configuration above into the mcp.json file that opens
03

Save the file

Cursor will automatically detect the new MCP server
04

Start using EBI Proteins API

Open Agent mode in chat and ask: "Using EBI Proteins API, help me...". 16 tools available

Why Use Cursor with the EBI Proteins API MCP Server

Cursor AI Code Editor provides unique advantages when paired with EBI Proteins API through the Model Context Protocol.

01

Agent mode turns Cursor into an autonomous coding assistant that can read files, run commands, and call MCP tools without switching context

02

Cursor's Composer feature can generate entire files using real-time data fetched through MCP. no copy-pasting from external dashboards

03

MCP tools appear alongside built-in tools like file reading and terminal access, creating a unified agentic environment

04

VS Code extension compatibility means your existing workflow, keybindings, and extensions all work alongside MCP tools

EBI Proteins API + Cursor Use Cases

Practical scenarios where Cursor combined with the EBI Proteins API MCP Server delivers measurable value.

01

Code generation with live data: ask Cursor to generate a security report module using live DNS and subdomain data fetched through MCP

02

Automated documentation: have Cursor query your API's tool schemas and generate TypeScript interfaces or OpenAPI specs automatically

03

Infrastructure-as-code: Cursor can fetch domain configurations and generate corresponding Terraform or CloudFormation templates

04

Test scaffolding: ask Cursor to pull real API responses via MCP and generate unit test fixtures from actual data

Example Prompts for EBI Proteins API in Cursor

Ready-to-use prompts you can give your Cursor agent to start working with EBI Proteins API immediately.

01

"Get all known genetic variants for the TP53 tumor suppressor protein."

02

"Show me the domain architecture and binding sites of the EGFR protein."

03

"Map the BRCA1 protein to its genome coordinates on GRCh38."

Troubleshooting EBI Proteins API MCP Server with Cursor

Common issues when connecting EBI Proteins API to Cursor through Vinkius, and how to resolve them.

01

Tools not appearing in Cursor

Ensure you are in Agent mode (not Ask mode). MCP tools only work in Agent mode.
02

Server shows as disconnected

Check Settings → Features → MCP and verify the server status. Try clicking the refresh button.

EBI Proteins API + Cursor FAQ

Common questions about integrating EBI Proteins API MCP Server with Cursor.

01

What is Agent mode and why does it matter for MCP?

Agent mode is Cursor's autonomous execution mode where the AI can perform multi-step tasks: reading files, editing code, running terminal commands, and calling MCP tools. Without Agent mode, Cursor operates in a simpler ask-and-answer mode that doesn't support tool calling. Always ensure you're in Agent mode when working with MCP servers.
02

Where does Cursor store MCP configuration?

Cursor looks for MCP server configurations in a mcp.json file. You can configure servers at the project level (.cursor/mcp.json in your project root) or globally (~/.cursor/mcp.json). Project-level configs take precedence.
03

Can Cursor use MCP tools in inline edits?

No. MCP tools are only available in Agent mode through the chat panel. Inline completions and Tab suggestions do not trigger MCP tool calls. This is by design. tool calls require user visibility and approval.
04

How do I verify MCP tools are loaded?

Open Settings → Features → MCP and look for your server name. A green indicator means the server is connected. You can also check Agent mode's available tools by clicking the tools dropdown in the chat panel.

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