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EBI Proteins API MCP Server for Claude CodeGive Claude Code instant access to 16 tools to Get Antigen, Get Coordinates, Get Genecentric, and more

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Claude Code is Anthropic's agentic CLI for terminal-first development. Add EBI Proteins API as an MCP server in one command and Claude Code will discover every tool at runtime. ideal for automation pipelines, CI/CD integration, and headless workflows via Vinkius.

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The EBI Proteins API MCP Server for Claude Code is a standout in the The Unthinkable category — giving your AI agent 16 tools to work with, ready to go from day one.

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Classic Setup·bash
# Your Vinkius token. get it at cloud.vinkius.com
claude mcp add ebi-proteins-api --transport http "https://edge.vinkius.com/[YOUR_TOKEN_HERE]/mcp"
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About EBI Proteins API MCP Server

Connect to the EMBL-EBI Proteins API and access comprehensive protein biology data from one of the world's leading bioinformatics institutes.

Claude Code registers EBI Proteins API as an MCP server in a single terminal command. Once connected, Claude Code discovers all 16 tools at runtime and can call them headlessly. ideal for CI/CD pipelines, cron jobs, and automated workflows where EBI Proteins API data drives decisions without human intervention.

What you can do

  • Protein Retrieval — Fetch complete protein entries by UniProt accession with names, organisms, gene information, sequences, and cross-references
  • Sequence Features — Retrieve annotated domains, binding sites, active sites, signal peptides, transmembrane regions, and disulfide bonds for any protein
  • Genetic Variants — Access curated variants from UniProtKB aggregated with large-scale studies including ClinVar, gnomAD, 1000 Genomes, COSMIC, and TOPMed
  • Proteomics & PTMs — Query mass-spectrometry peptide evidence and post-translational modifications from PeptideAtlas, MaxQB, EPD, and ProteomicsDB
  • Mutagenesis — Explore curated mutagenesis experiments with detailed phenotypic effect descriptions
  • Proteomes & Taxonomy — Search reference proteomes and navigate the taxonomy tree by ID or organism name
  • Genome Coordinates — Map proteins to genome positions on GRCh38/GRCh37 with Ensembl gene, transcript, and translation IDs

The EBI Proteins API MCP Server exposes 16 tools through the Vinkius. Connect it to Claude Code in under two minutes — credentials fully managed, no infrastructure to provision, no vendor lock-in. Your configuration, your data, your control.

All 16 EBI Proteins API tools available for Claude Code

When Claude Code connects to EBI Proteins API through Vinkius, your AI agent gets direct access to every tool listed below — spanning proteins, uniprot, bioinformatics, and more. Every call runs in a secure, isolated environment with full audit visibility. Beyond a simple connection, you get real-time monitoring of agent activity, enterprise governance, and optimized token usage.

get

Get antigen on EBI Proteins API

These are peptide regions used for antibody generation, indicating experimentally validated protein expression targets. Useful for immunology and antibody-based research. Get antigen sequences from Human Protein Atlas

get

Get coordinates on EBI Proteins API

Returns Ensembl gene, transcript, and translation IDs along with chromosome, start/end positions, and strand information. Essential for bridging protein annotations with genomic data. Get genome coordinate mappings for a protein

get

Get genecentric on EBI Proteins API

Shows canonical protein and related protein count for each gene. Use with a UniProt Proteome ID (e.g. UP000005640). Get the gene-centric view of a proteome

get

Get mutagenesis on EBI Proteins API

Each entry includes the wild-type and mutant residues, position, and a description of the functional impact. Critical for understanding structure-function relationships. Get mutagenesis experiments and phenotypic effects

get

Get protein on EBI Proteins API

Use a UniProt accession such as P12345, Q9Y6K9, or P53_HUMAN. Retrieve a full protein entry by UniProt accession

get

Get protein features on EBI Proteins API

Features include domains, binding sites, active sites, signal peptides, transmembrane regions, disulfide bonds, glycosylation sites, and more. Each feature has start/end positions and evidence counts. Get sequence feature annotations for a protein

get

Get proteome on EBI Proteins API

Returns taxonomy, protein count, gene count, reference status, and component information. Use IDs like UP000005640 for human proteome or UP000000589 for mouse. Get a specific proteome by UniProt Proteome ID

get

Get proteomics on EBI Proteins API

Shows which peptides have been experimentally detected and whether they are unique to this protein. Essential for validating protein expression. Get mass-spectrometry proteomics data for a protein

get

Get proteomics ptm on EBI Proteins API

Provides residue-level PTM positions with evidence counts. Get post-translational modifications from mass-spec data

get

Get taxonomy on EBI Proteins API

Returns scientific name, common name, rank, lineage, parent, and children nodes. Use IDs like 9606 for human, 10090 for mouse, 562 for E. coli. Get taxonomy node details by NCBI taxon ID

get

Get variation on EBI Proteins API

Each variant includes wild-type and mutant residues, clinical significance, consequence type (e.g. missense, nonsense), and cross-references. Critical for clinical genomics and variant interpretation. Get genetic variants for a protein from multiple sources

search

Search features by type on EBI Proteins API

Valid types include: DOMAIN, BINDING, ACTIVE_SITE, SIGNAL, TRANSMEM, DISULFID, CARBOHYD, MOD_RES, VARIANT, MUTAGEN, REGION, MOTIF, SITE, REPEAT, COILED, COMPBIAS, HELIX, STRAND, TURN. Search features by type across proteins

search

Search proteins on EBI Proteins API

You can combine gene name (e.g. TP53), organism (e.g. human, 9606), keyword (e.g. kinase), or accession. Returns a summarized list of matching proteins with names, organisms, and sequence lengths. Search proteins by gene name, organism, or keyword

search

Search proteomes on EBI Proteins API

Returns proteome IDs, taxonomy, protein counts, gene counts, and reference proteome status. Use queries like "homo sapiens", "escherichia coli", "arabidopsis". Search proteomes by organism name

search

Search taxonomy on EBI Proteins API

Returns matching taxonomy entries with scientific names, common names, taxon IDs, and ranks. Useful for finding the correct taxon ID before querying proteins or proteomes for a specific organism. Search taxonomy by organism name

search

Search variation on EBI Proteins API

g. large_scale_study, uniprot, mixed), consequence type (e.g. missense, stop gained), and wild-type residue. Use this to find clinically relevant variants across the proteome. Search variants by consequence type, source, or residue

Connect EBI Proteins API to Claude Code via MCP

Follow these steps to wire EBI Proteins API into Claude Code. The entire setup takes under two minutes — your credentials stay safe behind Vinkius.

01

Install Claude Code

Run npm install -g @anthropic-ai/claude-code if not already installed
02

Add the MCP Server

Run the command above in your terminal
03

Verify the connection

Run claude mcp to list connected servers, or type /mcp inside a session
04

Start using EBI Proteins API

Ask Claude: "Using EBI Proteins API, show me...". 16 tools are ready

Why Use Claude Code with the EBI Proteins API MCP Server

Claude Code provides unique advantages when paired with EBI Proteins API through the Model Context Protocol.

01

Single-command setup: `claude mcp add` registers the server instantly. no config files to edit or applications to restart

02

Terminal-native workflow means MCP tools integrate seamlessly into shell scripts, CI/CD pipelines, and automated DevOps tasks

03

Claude Code runs headlessly, enabling unattended batch processing using EBI Proteins API tools in cron jobs or deployment scripts

04

Built by the same team that created the MCP protocol, ensuring first-class compatibility and the fastest adoption of new protocol features

EBI Proteins API + Claude Code Use Cases

Practical scenarios where Claude Code combined with the EBI Proteins API MCP Server delivers measurable value.

01

CI/CD integration: embed EBI Proteins API tool calls in your deployment pipeline to validate configurations or fetch secrets before shipping

02

Headless batch processing: schedule Claude Code to query EBI Proteins API nightly and generate reports without human intervention

03

Shell scripting: pipe EBI Proteins API outputs into other CLI tools for data transformation, filtering, and aggregation

04

Infrastructure monitoring: run Claude Code in a cron job to query EBI Proteins API status endpoints and alert on anomalies

Example Prompts for EBI Proteins API in Claude Code

Ready-to-use prompts you can give your Claude Code agent to start working with EBI Proteins API immediately.

01

"Get all known genetic variants for the TP53 tumor suppressor protein."

02

"Show me the domain architecture and binding sites of the EGFR protein."

03

"Map the BRCA1 protein to its genome coordinates on GRCh38."

Troubleshooting EBI Proteins API MCP Server with Claude Code

Common issues when connecting EBI Proteins API to Claude Code through Vinkius, and how to resolve them.

01

Command not found: claude

Ensure Claude Code is installed globally: npm install -g @anthropic-ai/claude-code
02

Connection timeout

Check your internet connection and verify the Edge URL is reachable

EBI Proteins API + Claude Code FAQ

Common questions about integrating EBI Proteins API MCP Server with Claude Code.

01

How do I add an MCP server to Claude Code?

Run claude mcp add --transport http "" in your terminal. Claude Code registers the server and discovers all tools immediately.
02

Can Claude Code run MCP tools in headless mode?

Yes. Claude Code supports non-interactive execution, making it ideal for scripts, cron jobs, and CI/CD pipelines that need MCP tool access.
03

How do I list all connected MCP servers?

Run claude mcp in your terminal to see all registered servers and their status, or type /mcp inside an active Claude Code session.

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