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EBI Proteins API MCP Server for Vercel AI SDKGive Vercel AI SDK instant access to 16 tools to Get Antigen, Get Coordinates, Get Genecentric, and more

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The Vercel AI SDK is the TypeScript toolkit for building AI-powered applications. Connect EBI Proteins API through Vinkius and every tool is available as a typed function. ready for React Server Components, API routes, or any Node.js backend.

Ask AI about this MCP Server for Vercel AI SDK

The EBI Proteins API MCP Server for Vercel AI SDK is a standout in the The Unthinkable category — giving your AI agent 16 tools to work with, ready to go from day one.

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typescript
import { createMCPClient } from "@ai-sdk/mcp";
import { generateText } from "ai";
import { openai } from "@ai-sdk/openai";

async function main() {
  const mcpClient = await createMCPClient({
    transport: {
      type: "http",
      // Your Vinkius token. get it at cloud.vinkius.com
      url: "https://edge.vinkius.com/[YOUR_TOKEN_HERE]/mcp",
    },
  });

  try {
    const tools = await mcpClient.tools();
    const { text } = await generateText({
      model: openai("gpt-4o"),
      tools,
      prompt: "Using EBI Proteins API, list all available capabilities.",
    });
    console.log(text);
  } finally {
    await mcpClient.close();
  }
}

main();
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About EBI Proteins API MCP Server

Connect to the EMBL-EBI Proteins API and access comprehensive protein biology data from one of the world's leading bioinformatics institutes.

The Vercel AI SDK gives every EBI Proteins API tool full TypeScript type inference, IDE autocomplete, and compile-time error checking. Connect 16 tools through Vinkius and stream results progressively to React, Svelte, or Vue components. works on Edge Functions, Cloudflare Workers, and any Node.js runtime.

What you can do

  • Protein Retrieval — Fetch complete protein entries by UniProt accession with names, organisms, gene information, sequences, and cross-references
  • Sequence Features — Retrieve annotated domains, binding sites, active sites, signal peptides, transmembrane regions, and disulfide bonds for any protein
  • Genetic Variants — Access curated variants from UniProtKB aggregated with large-scale studies including ClinVar, gnomAD, 1000 Genomes, COSMIC, and TOPMed
  • Proteomics & PTMs — Query mass-spectrometry peptide evidence and post-translational modifications from PeptideAtlas, MaxQB, EPD, and ProteomicsDB
  • Mutagenesis — Explore curated mutagenesis experiments with detailed phenotypic effect descriptions
  • Proteomes & Taxonomy — Search reference proteomes and navigate the taxonomy tree by ID or organism name
  • Genome Coordinates — Map proteins to genome positions on GRCh38/GRCh37 with Ensembl gene, transcript, and translation IDs

The EBI Proteins API MCP Server exposes 16 tools through the Vinkius. Connect it to Vercel AI SDK in under two minutes — credentials fully managed, no infrastructure to provision, no vendor lock-in. Your configuration, your data, your control.

All 16 EBI Proteins API tools available for Vercel AI SDK

When Vercel AI SDK connects to EBI Proteins API through Vinkius, your AI agent gets direct access to every tool listed below — spanning proteins, uniprot, bioinformatics, and more. Every call runs in a secure, isolated environment with full audit visibility. Beyond a simple connection, you get real-time monitoring of agent activity, enterprise governance, and optimized token usage.

get

Get antigen on EBI Proteins API

These are peptide regions used for antibody generation, indicating experimentally validated protein expression targets. Useful for immunology and antibody-based research. Get antigen sequences from Human Protein Atlas

get

Get coordinates on EBI Proteins API

Returns Ensembl gene, transcript, and translation IDs along with chromosome, start/end positions, and strand information. Essential for bridging protein annotations with genomic data. Get genome coordinate mappings for a protein

get

Get genecentric on EBI Proteins API

Shows canonical protein and related protein count for each gene. Use with a UniProt Proteome ID (e.g. UP000005640). Get the gene-centric view of a proteome

get

Get mutagenesis on EBI Proteins API

Each entry includes the wild-type and mutant residues, position, and a description of the functional impact. Critical for understanding structure-function relationships. Get mutagenesis experiments and phenotypic effects

get

Get protein on EBI Proteins API

Use a UniProt accession such as P12345, Q9Y6K9, or P53_HUMAN. Retrieve a full protein entry by UniProt accession

get

Get protein features on EBI Proteins API

Features include domains, binding sites, active sites, signal peptides, transmembrane regions, disulfide bonds, glycosylation sites, and more. Each feature has start/end positions and evidence counts. Get sequence feature annotations for a protein

get

Get proteome on EBI Proteins API

Returns taxonomy, protein count, gene count, reference status, and component information. Use IDs like UP000005640 for human proteome or UP000000589 for mouse. Get a specific proteome by UniProt Proteome ID

get

Get proteomics on EBI Proteins API

Shows which peptides have been experimentally detected and whether they are unique to this protein. Essential for validating protein expression. Get mass-spectrometry proteomics data for a protein

get

Get proteomics ptm on EBI Proteins API

Provides residue-level PTM positions with evidence counts. Get post-translational modifications from mass-spec data

get

Get taxonomy on EBI Proteins API

Returns scientific name, common name, rank, lineage, parent, and children nodes. Use IDs like 9606 for human, 10090 for mouse, 562 for E. coli. Get taxonomy node details by NCBI taxon ID

get

Get variation on EBI Proteins API

Each variant includes wild-type and mutant residues, clinical significance, consequence type (e.g. missense, nonsense), and cross-references. Critical for clinical genomics and variant interpretation. Get genetic variants for a protein from multiple sources

search

Search features by type on EBI Proteins API

Valid types include: DOMAIN, BINDING, ACTIVE_SITE, SIGNAL, TRANSMEM, DISULFID, CARBOHYD, MOD_RES, VARIANT, MUTAGEN, REGION, MOTIF, SITE, REPEAT, COILED, COMPBIAS, HELIX, STRAND, TURN. Search features by type across proteins

search

Search proteins on EBI Proteins API

You can combine gene name (e.g. TP53), organism (e.g. human, 9606), keyword (e.g. kinase), or accession. Returns a summarized list of matching proteins with names, organisms, and sequence lengths. Search proteins by gene name, organism, or keyword

search

Search proteomes on EBI Proteins API

Returns proteome IDs, taxonomy, protein counts, gene counts, and reference proteome status. Use queries like "homo sapiens", "escherichia coli", "arabidopsis". Search proteomes by organism name

search

Search taxonomy on EBI Proteins API

Returns matching taxonomy entries with scientific names, common names, taxon IDs, and ranks. Useful for finding the correct taxon ID before querying proteins or proteomes for a specific organism. Search taxonomy by organism name

search

Search variation on EBI Proteins API

g. large_scale_study, uniprot, mixed), consequence type (e.g. missense, stop gained), and wild-type residue. Use this to find clinically relevant variants across the proteome. Search variants by consequence type, source, or residue

Connect EBI Proteins API to Vercel AI SDK via MCP

Follow these steps to wire EBI Proteins API into Vercel AI SDK. The entire setup takes under two minutes — your credentials stay safe behind Vinkius.

01

Install dependencies

Run npm install @ai-sdk/mcp ai @ai-sdk/openai
02

Replace the token

Replace [YOUR_TOKEN_HERE] with your Vinkius token
03

Run the script

Save to agent.ts and run with npx tsx agent.ts
04

Explore tools

The SDK discovers 16 tools from EBI Proteins API and passes them to the LLM

Why Use Vercel AI SDK with the EBI Proteins API MCP Server

Vercel AI SDK provides unique advantages when paired with EBI Proteins API through the Model Context Protocol.

01

TypeScript-first: every MCP tool gets full type inference, IDE autocomplete, and compile-time error checking out of the box

02

Framework-agnostic core works with Next.js, Nuxt, SvelteKit, or any Node.js runtime. same EBI Proteins API integration everywhere

03

Built-in streaming UI primitives let you display EBI Proteins API tool results progressively in React, Svelte, or Vue components

04

Edge-compatible: the AI SDK runs on Vercel Edge Functions, Cloudflare Workers, and other edge runtimes for minimal latency

EBI Proteins API + Vercel AI SDK Use Cases

Practical scenarios where Vercel AI SDK combined with the EBI Proteins API MCP Server delivers measurable value.

01

AI-powered web apps: build dashboards that query EBI Proteins API in real-time and stream results to the UI with zero loading states

02

API backends: create serverless endpoints that orchestrate EBI Proteins API tools and return structured JSON responses to any frontend

03

Chatbots with tool use: embed EBI Proteins API capabilities into conversational interfaces with streaming responses and tool call visibility

04

Internal tools: build admin panels where team members interact with EBI Proteins API through natural language queries

Example Prompts for EBI Proteins API in Vercel AI SDK

Ready-to-use prompts you can give your Vercel AI SDK agent to start working with EBI Proteins API immediately.

01

"Get all known genetic variants for the TP53 tumor suppressor protein."

02

"Show me the domain architecture and binding sites of the EGFR protein."

03

"Map the BRCA1 protein to its genome coordinates on GRCh38."

Troubleshooting EBI Proteins API MCP Server with Vercel AI SDK

Common issues when connecting EBI Proteins API to Vercel AI SDK through Vinkius, and how to resolve them.

01

createMCPClient is not a function

Install: npm install @ai-sdk/mcp

EBI Proteins API + Vercel AI SDK FAQ

Common questions about integrating EBI Proteins API MCP Server with Vercel AI SDK.

01

How does the Vercel AI SDK connect to MCP servers?

Import createMCPClient from @ai-sdk/mcp and pass the server URL. The SDK discovers all tools and provides typed TypeScript interfaces for each one.
02

Can I use MCP tools in Edge Functions?

Yes. The AI SDK is fully edge-compatible. MCP connections work on Vercel Edge Functions, Cloudflare Workers, and similar runtimes.
03

Does it support streaming tool results?

Yes. The SDK provides streaming primitives like useChat and streamText that handle tool calls and display results progressively in the UI.

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