EBI InterPro MCP Server for Vercel AI SDKGive Vercel AI SDK instant access to 16 tools to Get Cdd Entry, Get Clan, Get Entry, and more
GDPR Free for SubscribersThe Vercel AI SDK is the TypeScript toolkit for building AI-powered applications. Connect EBI InterPro through Vinkius and every tool is available as a typed function. ready for React Server Components, API routes, or any Node.js backend.
Ask AI about this MCP Server for Vercel AI SDK
The EBI InterPro MCP Server for Vercel AI SDK is a standout in the The Unthinkable category — giving your AI agent 16 tools to work with, ready to go from day one.
Vinkius delivers Streamable HTTP and SSE to any MCP client
Geminiimport { createMCPClient } from "@ai-sdk/mcp";
import { generateText } from "ai";
import { openai } from "@ai-sdk/openai";
async function main() {
const mcpClient = await createMCPClient({
transport: {
type: "http",
// Your Vinkius token. get it at cloud.vinkius.com
url: "https://edge.vinkius.com/[YOUR_TOKEN_HERE]/mcp",
},
});
try {
const tools = await mcpClient.tools();
const { text } = await generateText({
model: openai("gpt-4o"),
tools,
prompt: "Using EBI InterPro, list all available capabilities.",
});
console.log(text);
} finally {
await mcpClient.close();
}
}
main();
* Every MCP server runs on Vinkius-managed infrastructure inside AWS - a purpose-built runtime with per-request V8 isolates, Ed25519 signed audit chains, and sub-40ms cold starts optimized for native MCP execution. See our infrastructure
About EBI InterPro MCP Server
Connect to the InterPro API and access the world's most comprehensive resource for protein family, domain, and functional site classification.
The Vercel AI SDK gives every EBI InterPro tool full TypeScript type inference, IDE autocomplete, and compile-time error checking. Connect 16 tools through Vinkius and stream results progressively to React, Svelte, or Vue components. works on Edge Functions, Cloudflare Workers, and any Node.js runtime.
What you can do
- Domain Classification — Retrieve detailed InterPro entry information including family/domain descriptions, GO terms, and member database cross-references
- Multi-Database Access — Query entries from Pfam, CDD, SMART, Prosite, PANTHER, Gene3D, HAMAP, and more through a unified interface
- Protein Annotation — Find all InterPro domains, families, and sites annotated on any UniProt protein
- Structure Mapping — Discover PDB structures containing proteins that match specific InterPro entries
- Taxonomic Distribution — Explore which organisms contain proteins matching a domain or family — essential for evolutionary biology
- Proteome Coverage — Assess domain annotation coverage for complete proteomes
- Clan Analysis — Navigate Pfam clan hierarchies to understand super-family relationships
The EBI InterPro MCP Server exposes 16 tools through the Vinkius. Connect it to Vercel AI SDK in under two minutes — credentials fully managed, no infrastructure to provision, no vendor lock-in. Your configuration, your data, your control.
All 16 EBI InterPro tools available for Vercel AI SDK
When Vercel AI SDK connects to EBI InterPro through Vinkius, your AI agent gets direct access to every tool listed below — spanning interpro, pfam, protein-domains, and more. Every call runs in a secure, isolated environment with full audit visibility. Beyond a simple connection, you get real-time monitoring of agent activity, enterprise governance, and optimized token usage.
Get cdd entry on EBI InterPro
CDD provides curated models for protein domain families and includes additional alignment and structure data. Use accessions like cd00001. Get CDD (Conserved Domain Database) entry details
Get clan on EBI InterPro
Returns clan accession, name, description, and member counts. Use Pfam clan accessions like CL0001. Get Pfam clan (super-family grouping) details
Get entry on EBI InterPro
Returns name, type (family, domain, homologous superfamily, repeat, site), description, Gene Ontology terms, member database cross-references, and literature count. Use accessions like IPR000001, IPR036291. Get InterPro entry metadata for a family or domain
Get entry proteins on EBI InterPro
Returns protein accessions, names, lengths, and source organisms. Useful for finding all members of a protein family across the UniProt database. Get all proteins matching an InterPro entry
Get entry structures on EBI InterPro
Returns PDB IDs, names, experiment types, and resolutions. Useful for finding structural representatives of a protein family or domain. Get all PDB structures matching an InterPro entry
Get entry taxonomy on EBI InterPro
Returns taxonomy nodes with names, ranks, and protein counts. This answers the evolutionary biology question "which organisms have this domain/family?" and is essential for understanding protein evolution and conservation. Get taxonomic distribution of an InterPro entry
Get pfam entry on EBI InterPro
Pfam is the most widely used protein domain database. Use accessions like PF00069 (kinase domain), PF00076 (RRM domain). Get Pfam domain or family details
Get protein on EBI InterPro
Returns the protein name, length, source organism, evidence level, fragment status, and counters for how many InterPro entries, Pfam domains, structures, and taxa are associated with it. Get protein details with all domain and family assignments
Get protein entries on EBI InterPro
This is the key tool for understanding "what domains does my protein have?" — the fundamental question in protein characterization. Get all InterPro entries matching a specific protein
Get proteome on EBI InterPro
Returns proteome ID, organism name, strain, reference status, and counters for associated entries and proteins. Use UniProt proteome IDs like UP000005640 (human). Get proteome details with domain coverage statistics
Get structure on EBI InterPro
Use a 4-character PDB ID like 1cbs or 4hhb. Get a PDB structure with mapped InterPro annotations
Get taxonomy on EBI InterPro
Returns the organism name, rank, lineage, number of children taxa, and counters for associated InterPro entries and proteins. Use IDs like 9606 (human), 10090 (mouse), 562 (E. coli). Get taxonomic node with entry and protein counts
List entry databases on EBI InterPro
Shows the number of entries in each database. Useful for understanding the scope of available domain and family annotations. List all InterPro member databases and entry counts
Search entries on EBI InterPro
Optionally filter by entry type: family, domain, homologous_superfamily, repeat, or site. Returns accessions, names, types, and protein/structure counts. Use queries like "kinase", "zinc finger", "immunoglobulin". Search InterPro entries by keyword and type
Search proteins on EBI InterPro
Returns UniProt accessions, names, lengths, organisms, and annotation counts. Use queries like "insulin", "hemoglobin", "BRCA1". Search proteins in InterPro by name or keyword
Search taxonomy on EBI InterPro
Returns taxon IDs, names, ranks, and annotation counts. Use queries like "human", "drosophila", "arabidopsis", "saccharomyces". Search taxonomy by organism name
Connect EBI InterPro to Vercel AI SDK via MCP
Follow these steps to wire EBI InterPro into Vercel AI SDK. The entire setup takes under two minutes — your credentials stay safe behind Vinkius.
Install dependencies
npm install @ai-sdk/mcp ai @ai-sdk/openaiReplace the token
[YOUR_TOKEN_HERE] with your Vinkius tokenRun the script
agent.ts and run with npx tsx agent.tsExplore tools
Why Use Vercel AI SDK with the EBI InterPro MCP Server
Vercel AI SDK provides unique advantages when paired with EBI InterPro through the Model Context Protocol.
TypeScript-first: every MCP tool gets full type inference, IDE autocomplete, and compile-time error checking out of the box
Framework-agnostic core works with Next.js, Nuxt, SvelteKit, or any Node.js runtime. same EBI InterPro integration everywhere
Built-in streaming UI primitives let you display EBI InterPro tool results progressively in React, Svelte, or Vue components
Edge-compatible: the AI SDK runs on Vercel Edge Functions, Cloudflare Workers, and other edge runtimes for minimal latency
EBI InterPro + Vercel AI SDK Use Cases
Practical scenarios where Vercel AI SDK combined with the EBI InterPro MCP Server delivers measurable value.
AI-powered web apps: build dashboards that query EBI InterPro in real-time and stream results to the UI with zero loading states
API backends: create serverless endpoints that orchestrate EBI InterPro tools and return structured JSON responses to any frontend
Chatbots with tool use: embed EBI InterPro capabilities into conversational interfaces with streaming responses and tool call visibility
Internal tools: build admin panels where team members interact with EBI InterPro through natural language queries
Example Prompts for EBI InterPro in Vercel AI SDK
Ready-to-use prompts you can give your Vercel AI SDK agent to start working with EBI InterPro immediately.
"What domains and families does the human TP53 protein belong to?"
"Show me all member databases in InterPro and how many entries each has."
"Which organisms have the kinase domain PF00069?"
Troubleshooting EBI InterPro MCP Server with Vercel AI SDK
Common issues when connecting EBI InterPro to Vercel AI SDK through Vinkius, and how to resolve them.
createMCPClient is not a function
npm install @ai-sdk/mcpEBI InterPro + Vercel AI SDK FAQ
Common questions about integrating EBI InterPro MCP Server with Vercel AI SDK.
How does the Vercel AI SDK connect to MCP servers?
createMCPClient from @ai-sdk/mcp and pass the server URL. The SDK discovers all tools and provides typed TypeScript interfaces for each one.Can I use MCP tools in Edge Functions?
Does it support streaming tool results?
useChat and streamText that handle tool calls and display results progressively in the UI.Explore More MCP Servers
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